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OXT and TXNDC17
Number of citations of the paper that reports this interaction (PMID
14607844
)
12
Data Source:
HPRD
(in vitro)
OXT
TXNDC17
Gene Name
oxytocin/neurophysin I prepropeptide
thioredoxin domain containing 17
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Secretory Granule
Terminal Bouton
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Neurohypophyseal Hormone Activity
Oxytocin Receptor Binding
Peroxidase Activity
Protein Binding
Electron Carrier Activity
Protein-disulfide Reductase Activity
Biological Process
Response To Amphetamine
Regulation Of Heart Rate
Maternal Aggressive Behavior
Signal Transduction
Positive Regulation Of Cytosolic Calcium Ion Concentration
Heart Development
Female Pregnancy
Memory
Grooming Behavior
Response To Sucrose
Positive Regulation Of Norepinephrine Secretion
Response To Activity
Sleep
Response To Food
Positive Regulation Of Prostaglandin Secretion
Response To Estradiol
Response To Retinoic Acid
Response To Progesterone
Response To Prostaglandin E
Social Behavior
Negative Regulation Of Urine Volume
Positive Regulation Of Renal Sodium Excretion
Response To Cocaine
Hyperosmotic Salinity Response
Maternal Behavior
Sperm Ejaculation
Eating Behavior
Drinking Behavior
Response To Peptide Hormone
Response To Ether
Negative Regulation Of Blood Pressure
Positive Regulation Of Blood Pressure
Positive Regulation Of Ossification
Positive Regulation Of Female Receptivity
Positive Regulation Of Synaptic Transmission
Response To Glucocorticoid
Response To CAMP
Response To Electrical Stimulus
Regulation Of Sensory Perception Of Pain
Positive Regulation Of Synapse Assembly
Male Mating Behavior
Positive Regulation Of Penile Erection
Positive Regulation Of Hindgut Contraction
Negative Regulation Of Gastric Acid Secretion
Positive Regulation Of Uterine Smooth Muscle Contraction
Tumor Necrosis Factor-mediated Signaling Pathway
Oxidation-reduction Process
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Vasopressin-like receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Oxytocin
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
ESR2
KMT2A
OXTR
PREP
TXNDC17
8 interactors:
AVP
DYNLL1
EXOSC8
INS
OXT
RUFY1
TINF2
TXNRD1
Entrez ID
5020
84817
HPRD ID
08880
11656
Ensembl ID
ENSG00000101405
ENSG00000129235
Uniprot IDs
P01178
Q9BRA2
PDB IDs
1WOU
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cellular Response To Drug
Response To Anoxia
Positive Regulation Of Norepinephrine Secretion
Regulation Of Histone H3-K14 Acetylation
Regulation Of Cellular Response To Drug
Negative Regulation Of Gastric Acid Secretion
Regulation Of Response To Drug
Epithelial Cell Maturation Involved In Prostate Gland Development
Regulation Of Gastric Acid Secretion
Regulation Of Systemic Arterial Blood Pressure By Vasopressin
Hormone-mediated Apoptotic Signaling Pathway
Positive Regulation Of Penile Erection
Sperm Ejaculation
Maternal Process Involved In Parturition
Rhythmic Process
Regulation Of Penile Erection
Positive Regulation Of Catecholamine Secretion
Positive Regulation Of Uterine Smooth Muscle Contraction
Regulation Of Norepinephrine Secretion
Histone H3-K4 Trimethylation
Negative Regulation Of Androgen Receptor Signaling Pathway
Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Synaptic Transmission, GABAergic
Sleep
Maternal Behavior
Histone H4-K16 Acetylation
Vagina Development
Positive Regulation Of Histone H3-K4 Methylation
Insemination
Uterus Development
ERK1 And ERK2 Cascade
Parturition
Intracellular Estrogen Receptor Signaling Pathway
Epithelial Cell Differentiation Involved In Prostate Gland Development
Response To Steroid Hormone
Extracellular Negative Regulation Of Signal Transduction
Gland Development
Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To Organic Substance
Copulation
Epithelial Cell Maturation
Suckling Behavior
Positive Regulation Of Synaptic Transmission, Glutamatergic
Female Genitalia Development
Regulation Of Cellular Component Organization
Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Receptor Activity
Positive Regulation Of Smooth Muscle Contraction
Cellular Response To Hormone Stimulus
Peptidyl-lysine Trimethylation
Maternal Aggressive Behavior
Hyperosmotic Salinity Response
Aggressive Behavior
Regulation Of Cellular Component Organization
Regulation Of Female Receptivity
Maternal Behavior
Female Mating Behavior
Grooming Behavior
Regulation Of Renal Sodium Excretion
Copulation
Hyperosmotic Response
Regulation Of Excretion
Homeostatic Process
Mating Behavior
Positive Regulation Of Transport
Response To Salt Stress
Positive Regulation Of Blood Pressure
Social Behavior
Positive Regulation Of Secretion
Mating
Regulation Of Organelle Organization
Regulation Of Neurological System Process
Positive Regulation Of Lipid Biosynthetic Process
Regulation Of Cellular Localization
Positive Regulation Of Organelle Organization
Negative Regulation Of Protein ADP-ribosylation
Positive Regulation Of Hindgut Contraction
Regulation Of Fatty Acid Metabolic Process
Response To Osmotic Stress
Regulation Of Mitochondrion Organization
Renal System Process
Regulation Of Protein ADP-ribosylation
Negative Regulation Of Glycogen Catabolic Process
Regulation Of Hindgut Contraction
Ion Homeostasis
Positive Regulation Of Cell Growth
Regulation Of DNA Replication
Regulation Of Lipid Biosynthetic Process
Regulation Of Anion Transport
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Negative Regulation Of NAD(P)H Oxidase Activity
Regulation Of Secretion
Positive Regulation Of DNA Metabolic Process
Response To Alkaloid
Regulation Of Carbohydrate Metabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cellular Homeostasis
Regulation Of Ion Homeostasis
Positive Regulation Of Cellular PH Reduction
Positive Regulation Of Norepinephrine Secretion
Tagcloud
?
altering
anorexigenic
arcuate
basel
broader
dmnv
fos
hyperphagia
hypothalamus
icv
immunoreactive
intake
intraperitoneal
ip
islets
karger
locomotor
medulla
nasal
nts
oxytocin
paraventricular
postrema
potentiated
pvn
route
solitary
tolerance
vagus
Tagcloud (Difference)
?
altering
anorexigenic
arcuate
basel
broader
dmnv
fos
hyperphagia
hypothalamus
icv
immunoreactive
intake
intraperitoneal
ip
islets
karger
locomotor
medulla
nasal
nts
oxytocin
paraventricular
postrema
potentiated
pvn
route
solitary
tolerance
vagus
Tagcloud (Intersection)
?