OXT

Description		oxytocin/neurophysin I prepropeptide
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Secretory Granule Terminal Bouton Neuronal Dense Core Vesicle
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Neurohypophyseal Hormone Activity Protein Binding Oxytocin Receptor Binding
	Biological Process	Response To Amphetamine Regulation Of Heart Rate Maternal Aggressive Behavior Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Memory Grooming Behavior Response To Sucrose Positive Regulation Of Norepinephrine Secretion Response To Activity Response To Food Positive Regulation Of Prostaglandin Secretion Response To Estradiol Response To Retinoic Acid Response To Progesterone Response To Genistein Response To Prostaglandin E Social Behavior Intracellular Signal Transduction Negative Regulation Of Urine Volume Response To Cocaine Maternal Behavior Sperm Ejaculation Eating Behavior Drinking Behavior Response To Peptide Hormone Response To Ether Negative Regulation Of Blood Pressure Positive Regulation Of Blood Pressure Positive Regulation Of Ossification Positive Regulation Of Female Receptivity Response To Steroid Hormone Positive Regulation Of Synaptic Transmission Response To Glucocorticoid Response To CAMP Response To Electrical Stimulus Positive Regulation Of Synapse Assembly Male Mating Behavior Positive Regulation Of Penile Erection Positive Regulation Of Hindgut Contraction Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis
Pathways		Vasopressin-like receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Serum oxytocin levels ( 31361301)
Interacting Genes		5 interacting genes: ESR2 KMT2A OXTR PREP TXNDC17
Entrez ID		5020
HPRD ID		08880
Ensembl ID		ENSG00000101405
Uniprot IDs		P01178 X5D7M6
PDB IDs		7OFG 7OTD 7QVM 7RYC
Enriched GO Terms of Interacting Partners?		Nuclear Estrogen Receptor Activity T-helper 2 Cell Differentiation Unmethylated CpG Binding Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Protein-cysteine Methyltransferase Activity MLL1/2 Complex Negative Regulation Of Heterochromatin Formation Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity Minor Groove Of Adenine-thymine-rich DNA Binding Regulation Of Heterochromatin Formation Maternal Process Involved In Parturition Vasopressin Receptor Activity Oxytocin Receptor Activity Regulation Of Systemic Arterial Blood Pressure By Vasopressin Oligopeptidase Activity Protein-disulfide Reductase [NAD(P)H] Activity Estrogen Response Element Binding
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