CLDN11 and TSPAN4

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		CLDN11	TSPAN4
Description		claudin 11	tetraspanin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Neurofilament Plasma Membrane Bicellular Tight Junction Membrane Cell Junction Axon Basal Part Of Cell Tight Junction Anchoring Junction	Plasma Membrane Focal Adhesion Membrane Vesicle
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Antigen Binding Integrin Binding Protein Binding
	Biological Process	Cell Adhesion Spermatogenesis Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Tight Junction Assembly	Protein-containing Complex Assembly
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Blood glucose levels ( 31928498) Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) ( 28820441) Prostate cancer ( 21743467)	Falling risk ( 32999390)
Interacting Genes		12 interacting genes: AMIGO1 C16orf54 FNDC9 KLRC1 SHISA3 SMIM3 SPINT1 TMEM80 TNFSF14 TSPAN3 TSPAN4 ZP3	49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3
Entrez ID		5010	7106
HPRD ID		03207	04033
Ensembl ID		ENSG00000013297	ENSG00000214063
Uniprot IDs		O75508	A8MVV6 O14817
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Keratinization Epidermis Development Keratin Filament Intermediate Filament Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Myoblast Fusion Involved In Skeletal Muscle Regeneration Myoblast Fusion Integrin Complex Cellular Response To Low-density Lipoprotein Particle Stimulus Cellular Response To Lipoprotein Particle Stimulus Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Cerebellar Climbing Fiber To Purkinje Cell Synapse Identical Protein Binding CAMP Response Element Binding Regulation Of Cell Motility Hair Cycle Regulation Of Locomotion Integrin Binding Mesodermal Cell Differentiation Tissue Development
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