ATP12A and PPIB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ATP12A	PPIB
Gene Name		ATPase, H+/K+ transporting, nongastric, alpha polypeptide	peptidylprolyl isomerase B (cyclophilin B)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Hydrogen:potassium-exchanging ATPase Complex Basolateral Plasma Membrane	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Macromolecular Complex Melanosome Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Sodium:potassium-exchanging ATPase Activity ATP Binding Hydrogen:potassium-exchanging ATPase Activity Metal Ion Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Collagen Binding Protein Complex Binding Peptide Binding Poly(A) RNA Binding Unfolded Protein Binding RNA Polymerase Binding
	Biological Process	Potassium Ion Transport Regulation Of PH Metabolic Process Ion Transmembrane Transport Sodium Ion Transmembrane Transport Potassium Ion Homeostasis Transmembrane Transport Hydrogen Ion Transmembrane Transport	Protein Peptidyl-prolyl Isomerization Extracellular Matrix Organization Positive Regulation Of Multicellular Organism Growth Positive Regulation By Host Of Viral Process Positive Regulation By Host Of Viral Genome Replication Protein Stabilization Bone Development Chaperone-mediated Protein Folding Regulation Of Post-translational Protein Modification
Pathways		Ion transport by P-type ATPases Ion channel transport	Collagen formation Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: GNAI3 NPY PPIB	15 interactors: APOB ATP12A BANP CAMLG DNM2 HIST3H3 IRF3 MDM2 PEX19 PRL SGTA STAT5A UBQLN1 UBQLN4 VKORC1
Entrez ID		479	5479
HPRD ID		01667	00458
Ensembl ID		ENSG00000075673	ENSG00000166794
Uniprot IDs		B4E0R9 P54707	P23284
PDB IDs			1CYN 3ICH 3ICI
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Appetite Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Adult Feeding Behavior Synaptic Transmission Regulation Of Response To Food Regulation Of Appetite Positive Regulation Of Viral Genome Replication Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Interaction With Symbiont Cell-cell Signaling Negative Regulation Of Nucleotide Metabolic Process Vesicle Fusion Positive Regulation Of Multicellular Organism Growth G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Chaperone-mediated Protein Folding Regulation Of Cyclase Activity Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Organelle Fusion Protein Peptidyl-prolyl Isomerization Regulation Of CAMP Biosynthetic Process Protein Stabilization Neuropeptide Signaling Pathway Feeding Behavior Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Central Nervous System Neuron Development Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Membrane Fusion Regulation Of Protein Stability Regulation Of Viral Process Positive Regulation Of Developmental Growth Cerebral Cortex Development Adult Behavior	Positive Regulation Of Mitotic Cell Cycle JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Response To Growth Hormone Viral Process Regulation Of Body Fluid Levels Cellular Response To Hormone Stimulus JAK-STAT Cascade Positive Regulation Of Mitotic Cell Cycle Phase Transition Lactation Positive Regulation Of Cell Cycle Phase Transition Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Cycle Negative Regulation Of Lipid Binding Negative Regulation Of Interferon-beta Biosynthetic Process Cellular Response To UV-C Positive Regulation Of Mast Cell Differentiation Cellular Response To Vitamin B1 Regulation Of Developmental Growth Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Receptor Metabolic Process Immune System Process Negative Regulation Of Membrane Tubulation MDA-5 Signaling Pathway Macrophage Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Steroid Metabolic Process Regulation Of Multicellular Organism Growth Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Mast Cell Differentiation Development Of Secondary Male Sexual Characteristics Regulation Of Mitotic Cell Cycle Regulation Of Cytokine Biosynthetic Process Body Fluid Secretion Cellular Response To Lipid Cellular Response To Oxygen Levels Response To Hormone Traversing Start Control Point Of Mitotic Cell Cycle Peroxisome Membrane Biogenesis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Negative Regulation Of Mast Cell Apoptotic Process Response To Vitamin B1 Response To Ether Negative Regulation Of Defense Response To Virus By Host
Tagcloud ?			abeta abundance accompanies ad animal biomarkers cytokines diverse elisa immunostaining isotope key labeling lack lc microglia microglial ms nervous neurodegenerative neuroinflammation pdia3 pdia6 proper proteomic resident serpinh1 silac validation
Tagcloud (Difference) ?			abeta abundance accompanies ad animal biomarkers cytokines diverse elisa immunostaining isotope key labeling lack lc microglia microglial ms nervous neurodegenerative neuroinflammation pdia3 pdia6 proper proteomic resident serpinh1 silac validation
Tagcloud (Intersection) ?