ATP12A and NPY

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ATP12A	NPY
Gene Name		ATPase, H+/K+ transporting, nongastric, alpha polypeptide	neuropeptide Y
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Hydrogen:potassium-exchanging ATPase Complex Basolateral Plasma Membrane	Extracellular Region Extracellular Space Cell Golgi Apparatus
	Molecular Function	Sodium:potassium-exchanging ATPase Activity ATP Binding Hydrogen:potassium-exchanging ATPase Activity Metal Ion Binding	G-protein Coupled Receptor Activity Receptor Binding Neuropeptide Hormone Activity Calcium Channel Regulator Activity Neuropeptide Y Receptor Binding
	Biological Process	Potassium Ion Transport Regulation Of PH Metabolic Process Ion Transmembrane Transport Sodium Ion Transmembrane Transport Potassium Ion Homeostasis Transmembrane Transport Hydrogen Ion Transmembrane Transport	Calcium Ion Transport Movement Of Cell Or Subcellular Component G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Digestion Behavior Feeding Behavior Blood Circulation Regulation Of Blood Pressure Cell Proliferation Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Regulation Of Appetite Positive Regulation Of Appetite
Pathways		Ion transport by P-type ATPases Ion channel transport	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Periodontitis ( 23459936)
Protein-Protein Interactions		3 interactors: GNAI3 NPY PPIB	15 interactors: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1
Entrez ID		479	4852
HPRD ID		01667	01214
Ensembl ID		ENSG00000075673	ENSG00000122585
Uniprot IDs		B4E0R9 P54707	A4D158 P01303
PDB IDs			1QFA 1RON
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Appetite Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Adult Feeding Behavior Synaptic Transmission Regulation Of Response To Food Regulation Of Appetite Positive Regulation Of Viral Genome Replication Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Interaction With Symbiont Cell-cell Signaling Negative Regulation Of Nucleotide Metabolic Process Vesicle Fusion Positive Regulation Of Multicellular Organism Growth G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Chaperone-mediated Protein Folding Regulation Of Cyclase Activity Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Organelle Fusion Protein Peptidyl-prolyl Isomerization Regulation Of CAMP Biosynthetic Process Protein Stabilization Neuropeptide Signaling Pathway Feeding Behavior Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Central Nervous System Neuron Development Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Membrane Fusion Regulation Of Protein Stability Regulation Of Viral Process Positive Regulation Of Developmental Growth Cerebral Cortex Development Adult Behavior	Neuropeptide Signaling Pathway Feeding Behavior Cell-cell Signaling Synaptic Transmission G-protein Coupled Receptor Signaling Pathway Behavior Digestion Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Transport Negative Regulation Of Secretion Negative Regulation Of Feeding Behavior Outflow Tract Morphogenesis Peptide Hormone Secretion Peptide Secretion Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Hormone Secretion Regulation Of CAMP Biosynthetic Process Hormone Transport Cell Surface Receptor Signaling Pathway Peptide Transport Signal Transduction Regulation Of Secretion Regulation Of CAMP Metabolic Process Regulation Of Feeding Behavior Cellular Response To Stimulus Cardiac Left Ventricle Morphogenesis Response To Stimulus Membrane Depolarization Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Response To Food Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Signaling Positive Regulation Of Circadian Rhythm Amide Transport Regulation Of Appetite Cell Communication Multicellular Organismal Reproductive Process G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Multicellular Organism Reproduction Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Sensory Perception Of Pain Chemical Homeostasis Negative Regulation Of Secretion By Cell Metal Ion Homeostasis Cytosolic Calcium Ion Homeostasis Regulation Of Behavior Negative Regulation Of Insulin Secretion Regulation Of Cellular Localization
Tagcloud ?			anesthetized arch bischoff calciuresis concomitantly converting decline denervation diuresis excretion icatibant infusion intrarenal losartan magnified mediator michel micrograms microliter micromol mmhg modify natriuresis neuronally neuropeptide pflugers ramiprilat renovascular tubular
Tagcloud (Difference) ?			anesthetized arch bischoff calciuresis concomitantly converting decline denervation diuresis excretion icatibant infusion intrarenal losartan magnified mediator michel micrograms microliter micromol mmhg modify natriuresis neuronally neuropeptide pflugers ramiprilat renovascular tubular
Tagcloud (Intersection) ?