RFX1 and TADA3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RFX1	TADA3
Gene Name		regulatory factor X, 1 (influences HLA class II expression)	transcriptional adaptor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Intracellular Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Protein Domain Specific Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response	Regulation Of Protein Phosphorylation Chromatin Organization Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Nuclear Division Positive Regulation Of Gene Expression Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3	27 interactors: ADPGK ANKRD12 AR CCDC101 CCNC EIF3J EP300 ESR1 FAM107B HEXIM2 HIST3H3 HSPA8 ING5 KDM1A MAGEH1 NR1I2 PIAS4 RARA RFX1 RXRA SAP18 TADA2A TP53 TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		5989	10474
HPRD ID		02476	04252
Ensembl ID		ENSG00000132005	ENSG00000171148
Uniprot IDs		P22670	A8K899 O75528
PDB IDs		1DP7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Hindbrain Development Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development BMP Signaling Pathway Regulation Of Binding System Development SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Multicellular Organismal Development Mesonephros Development Biosynthetic Process Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transforming Growth Factor Beta Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Steroid Hormone Mediated Signaling Pathway Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Chromatin Organization Prostate Gland Development Cellular Response To Steroid Hormone Stimulus Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone Acetylation Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Internal Peptidyl-lysine Acetylation Response To Steroid Hormone
Tagcloud ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb mtmr14 overlap presents prove respect rise seizures srgap3 syndrome terminus typical
Tagcloud (Difference) ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	3p anomalies arm camk1 congenital creld1 define deleted deletion deletions features give handicap interstitial involve kb lengths mb mtmr14 overlap presents prove respect rise seizures srgap3 syndrome terminus typical
Tagcloud (Intersection) ?