RFX1 and HIVEP2

Number of citations: 44 (PubMedID 10642512)
Data Source: HPRD (in vivo)

		RFX1	HIVEP2
Name		regulatory factor X1	HIVEP zinc finger 2
Structure			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Immune Response	Regulation Of Transcription By RNA Polymerase II
GWAS		No GWAS studies recorded	Adiponectin levels ( 24105470 ) Adult body size ( 32376654 ) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686 ) Age at first birth ( 34211149 ) Asthma ( 32296059 ) Bipolar disorder ( 31043756 ) Coronary artery disease ( 29212778 ) Daytime sleep phenotypes ( 27126917 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Gastroesophageal reflux disease ( 34187846 ) HDL cholesterol levels ( 32203549 ) Hemoglobin ( 32888494 ) IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391 ) Mood instability ( 31168069 ) Pit-and-Fissure caries ( 24556642 ) Platelet distribution width ( 32888494 ) Type 2 diabetes ( 32499647 ) Weight ( 28552196 )
Novel Interactors		1 novel interactors: PRKACA	1 novel interactors: PAX6
Interacting Genes		14 interacting genes: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3	8 interacting genes: BRWD1 BTG3 CREBBP LINC01554 MTNR1A RFX1 RSPH1 YWHAE
Entrez ID		5989	3097
HPRD ID		02476	00881
Ensembl ID		ENSG00000132005	ENSG00000010818
Uniprot IDs		P22670	P31629
PDB IDs		1DP7	Not available
GO Terms Enriched among Interactors		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Heteromeric SMAD Protein Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process I-SMAD Binding Positive Regulation Of Macromolecule Metabolic Process Nucleus BMP Signaling Pathway DNA-templated Transcription Regulation Of Macromolecule Metabolic Process SMAD Protein Signal Transduction Regulation Of Metabolic Process Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Developmental Process Sequence-specific Double-stranded DNA Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Nucleic Acid Metabolic Process Supercoiled DNA Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Negative Regulation Of Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Bubble DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Intracellular Iron Ion Homeostasis Regulation Of Multicellular Organismal Process	None