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ELSPBP1 and PSMD9
Number of citations of the paper that reports this interaction (PMID
25009770
)
0
Data Source:
BioGRID
(pull down, unspecified method)
ELSPBP1
PSMD9
Gene Name
epididymal sperm binding protein 1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Proteasome Regulatory Particle
Proteasome Regulatory Particle, Base Subcomplex
Molecular Function
Transcription Coactivator Activity
Protein Binding
BHLH Transcription Factor Binding
Biological Process
Single Fertilization
G1/S Transition Of Mitotic Cell Cycle
Protein Polyubiquitination
Mitotic Cell Cycle
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cellular Amino Acid Metabolic Process
Apoptotic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Gene Expression
Viral Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Insulin Secretion
Cellular Nitrogen Compound Metabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Secretion
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Proteasome Regulatory Particle Assembly
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Hedgehog 'off' state
misspliced GSK3beta mutants stabilize beta-catenin
Hh ligand biogenesis disease
T41 mutants of beta-catenin aren't phosphorylated
Downstream signaling events of B Cell Receptor (BCR)
Degradation of beta-catenin by the destruction complex
Stabilization of p53
S33 mutants of beta-catenin aren't phosphorylated
AXIN mutants destabilize the destruction complex, activating WNT signaling
Removal of licensing factors from origins
Switching of origins to a post-replicative state
Mitotic G1-G1/S phases
Regulation of mRNA stability by proteins that bind AU-rich elements
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
DNA Replication Pre-Initiation
S45 mutants of beta-catenin aren't phosphorylated
APC/C:Cdc20 mediated degradation of mitotic proteins
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
deletions in the AMER1 gene destabilize the destruction complex
Autodegradation of the E3 ubiquitin ligase COP1
AMER1 mutants destabilize the destruction complex
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
PCP/CE pathway
Adaptive Immune System
CDK-mediated phosphorylation and removal of Cdc6
Hedgehog ligand biogenesis
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Separation of Sister Chromatids
HIV Infection
Ubiquitin-dependent degradation of Cyclin D
APC truncation mutants have impaired AXIN binding
Assembly of the pre-replicative complex
Autodegradation of Cdh1 by Cdh1:APC/C
p53-Dependent G1 DNA Damage Response
S37 mutants of beta-catenin aren't phosphorylated
XAV939 inhibits tankyrase, stabilizing AXIN
p53-Independent DNA Damage Response
p53-Independent G1/S DNA damage checkpoint
G1/S DNA Damage Checkpoints
Vpu mediated degradation of CD4
Synthesis of DNA
M/G1 Transition
Ubiquitin-dependent degradation of Cyclin D1
TCF dependent signaling in response to WNT
SCF-beta-TrCP mediated degradation of Emi1
degradation of AXIN
Signaling by Hedgehog
Regulation of mitotic cell cycle
Degradation of GLI1 by the proteasome
degradation of DVL
Cell Cycle Checkpoints
Signaling by WNT in cancer
GLI3 is processed to GLI3R by the proteasome
Regulation of Apoptosis
Degradation of GLI2 by the proteasome
Signaling by the B Cell Receptor (BCR)
Vif-mediated degradation of APOBEC3G
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
p53-Dependent G1/S DNA damage checkpoint
truncated APC mutants destabilize the destruction complex
TCF7L2 mutants don't bind CTBP
Signaling by Wnt
Cyclin E associated events during G1/S transition
APC/C:Cdc20 mediated degradation of Securin
AUF1 (hnRNP D0) destabilizes mRNA
CDK-mediated phosphorylation and removal of Cdc6
RNF mutants show enhanced WNT signaling and proliferation
G1/S Transition
truncations of AMER1 destabilize the destruction complex
Processing-defective Hh variants abrogate ligand secretion
Host Interactions of HIV factors
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex
Regulation of activated PAK-2p34 by proteasome mediated degradation
AXIN missense mutants destabilize the destruction complex
S Phase
APC/C-mediated degradation of cell cycle proteins
Cyclin A:Cdk2-associated events at S phase entry
SCF(Skp2)-mediated degradation of p27/p21
Mitotic Metaphase and Anaphase
Regulation of ornithine decarboxylase (ODC)
Antigen processing: Ubiquitination & Proteasome degradation
Orc1 removal from chromatin
Mitotic Anaphase
M Phase
APC truncation mutants are not K63 polyubiquitinated
Metabolism of amino acids and derivatives
Hedgehog 'on' state
Programmed Cell Death
Class I MHC mediated antigen processing & presentation
Regulation of DNA replication
Cell Cycle, Mitotic
beta-catenin independent WNT signaling
Orc1 removal from chromatin
Activation of NF-kappaB in B cells
Asymmetric localization of PCP proteins
deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling
Cross-presentation of soluble exogenous antigens (endosomes)
Antigen processing-Cross presentation
CDT1 association with the CDC6:ORC:origin complex
ER-Phagosome pathway
Drugs
Diseases
GWAS
Intelligence (
22449649
)
Protein-Protein Interactions
8 interactors:
MYF5
MYF6
MYOD1
MYOG
NEDD9
PSMD4
PSMD9
TAL1
17 interactors:
AHCYL1
BANP
BRCA1
CCDC136
CKS1B
CSH1
DCLRE1C
ELSPBP1
NCKIPSD
PSMC3
PSMC6
SKP2
TCF3
TNIP2
TRIM39
TRIM42
YY1
Entrez ID
64100
5715
HPRD ID
12119
04394
Ensembl ID
ENSG00000169393
ENSG00000110801
Uniprot IDs
Q96BH3
O00233
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Skeletal Muscle Fiber Development
Muscle Cell Fate Commitment
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Myoblast Fusion
Regulation Of Skeletal Muscle Fiber Development
Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
Regulation Of Myoblast Fusion
Positive Regulation Of Skeletal Muscle Tissue Development
Positive Regulation Of Myotube Differentiation
Regulation Of Myoblast Differentiation
Regulation Of Myotube Differentiation
Skeletal Muscle Cell Differentiation
Positive Regulation Of Striated Muscle Cell Differentiation
Positive Regulation Of Striated Muscle Tissue Development
Positive Regulation Of Muscle Tissue Development
Regulation Of Skeletal Muscle Tissue Development
Positive Regulation Of Muscle Cell Differentiation
Cell Fate Commitment
Regulation Of Striated Muscle Cell Differentiation
Regulation Of Striated Muscle Tissue Development
Skeletal Muscle Tissue Development
Skeletal Muscle Organ Development
Regulation Of Muscle Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Muscle Organ Development
Positive Regulation Of Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Striated Muscle Tissue Development
Muscle Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Muscle Tissue Development
Regulation Of Cell Development
Positive Regulation Of Cell Differentiation
Transcription From RNA Polymerase II Promoter
Regulation Of Cell Cycle Arrest
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Gene Expression
Positive Regulation Of Cell Development
Muscle Structure Development
Cellular Response To Estradiol Stimulus
Skeletal Muscle Fiber Development
Skeletal Muscle Tissue Regeneration
Cellular Response To Estrogen Stimulus
Myotube Cell Development
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Differentiation
G1/S Transition Of Mitotic Cell Cycle
Protein Polyubiquitination
Regulation Of Protein Ubiquitination
DNA Recombination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle Arrest
DNA Damage Response, Signal Transduction By P53 Class Mediator
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cell Cycle
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Regulation Of Cell Cycle Arrest
Negative Regulation Of Protein Ubiquitination
Signal Transduction By P53 Class Mediator
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Protein Catabolic Process
Double-strand Break Repair
Cell Cycle
V(D)J Recombination
Cellular Response To DNA Damage Stimulus
DNA Damage Checkpoint
Negative Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Process
Apoptotic Process
Programmed Cell Death
Cell Cycle Process
Regulation Of Mitotic Cell Cycle Phase Transition
Cell Death
Death
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Mitotic Cell Cycle Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Tagcloud
?
acetyltransferase
adenoviral
augment
augments
bridge
cipitation
coactivators
coregulator
e12
e1a
e47
encompass
gst
h2
helix
histidine
homeodomain
immunopre
interrupts
mutagenesis
pdx
pdz
pull
sequestration
suppresses
transcriptional
transferase
trichostatin
unable
Tagcloud (Difference)
?
acetyltransferase
adenoviral
augment
augments
bridge
cipitation
coactivators
coregulator
e12
e1a
e47
encompass
gst
h2
helix
histidine
homeodomain
immunopre
interrupts
mutagenesis
pdx
pdz
pull
sequestration
suppresses
transcriptional
transferase
trichostatin
unable
Tagcloud (Intersection)
?