DRG1 and CAPNS1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DRG1	CAPNS1
Gene Name		developmentally regulated GTP binding protein 1	calpain, small subunit 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Polysome Membrane	Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding GTP Binding Transcription Factor Binding Identical Protein Binding	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development	Proteolysis Positive Regulation Of Cell Proliferation Extracellular Matrix Disassembly Extracellular Matrix Organization
Pathways			Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CAPNS1 CLDN1 COIL LYL1 PHC2 RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15	18 interactors: AGTRAP ARHGEF6 ARR3 ATP5J2 CAPN1 CAPN2 CAST CDK4 DRG1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5
Entrez ID		4733	826
HPRD ID		16034	00240
Ensembl ID		ENSG00000185721	ENSG00000126247
Uniprot IDs		Q9Y295	P04632
PDB IDs		2EKI	1KFU 1KFX
Enriched GO Terms of Interacting Partners?		Definitive Hemopoiesis Hemangioblast Cell Differentiation Nuclear Speck Organization Positive Regulation Of SUMO Transferase Activity Positive Regulation Of Chromatin Assembly Or Disassembly Anatomical Structure Formation Involved In Morphogenesis Basophil Differentiation Blood Vessel Development Vasculature Development	Negative Regulation Of Glycolytic Process Signal Transduction Response To Hypoxia Regulation Of Cell Death Cellular Response To Stimulus Signaling Cell Communication Temperature Homeostasis Regulation Of Glycolytic Process Response To Stimulus Regulation Of Apoptotic Process Response To Drug Positive Regulation Of Cell Cycle Process Cellular Response To Nitrite Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Energy Derivation By Oxidation Of Organic Compounds Regulation Of Generation Of Precursor Metabolites And Energy Response To Organic Substance Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Interleukin-7-mediated Signaling Pathway Positive Regulation Of ATP Biosynthetic Process Positive Regulation Of Mitochondrial DNA Metabolic Process Cellular Response To Organic Substance Response To Stress Mitotic Cell Cycle Positive Regulation Of Energy Homeostasis Response To Statin Telomeric Loop Formation Age-dependent Telomere Shortening Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cell Proliferation Response To Organonitrogen Compound Interleukin-8 Production Telomere Maintenance Via Telomere Shortening Interleukin-2-mediated Signaling Pathway Positive Regulation Of Cellular Respiration Cellular Response To Oxygen Levels Respiratory Electron Transport Chain Response To Amino Acid Generation Of Precursor Metabolites And Energy Positive Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process Cell Division Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Endomembrane System Organization
Tagcloud ?		carrying cc cd36 cg colon crc dscr1 dscr1rs6517239 endpoint generating genotype germline interesting japanese lep nfkb ngal norris obesity polymorphisms ppar pparrs1801282 probability recurrence regia se sided stronger univariate	afp buffalo cadaveric calpain cd34 curing facilitates fetoprotein greatest hcc hepatectomy hepatoma implantation invasiveness largest lungs microscopic microvessel modalities occult partial project regeneration remnant resection resections sizes transplantation vegfr2
Tagcloud (Difference) ?		carrying cc cd36 cg colon crc dscr1 dscr1rs6517239 endpoint generating genotype germline interesting japanese lep nfkb ngal norris obesity polymorphisms ppar pparrs1801282 probability recurrence regia se sided stronger univariate	afp buffalo cadaveric calpain cd34 curing facilitates fetoprotein greatest hcc hepatectomy hepatoma implantation invasiveness largest lungs microscopic microvessel modalities occult partial project regeneration remnant resection resections sizes transplantation vegfr2
Tagcloud (Intersection) ?