DRG1 and LYL1

Number of citations of the paper that reports this interaction (PMID 8649774)
8

Data Source:
HPRD (in vitro)

		DRG1	LYL1
Gene Name		developmentally regulated GTP binding protein 1	lymphoblastic leukemia associated hematopoiesis regulator 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Polysome Membrane	Nucleus
	Molecular Function	Protein Binding GTP Binding Transcription Factor Binding Identical Protein Binding	DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development	Blood Vessel Maturation Transcription, DNA-templated Regulation Of Transcription, DNA-templated B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CAPNS1 CLDN1 COIL LYL1 PHC2 RWDD1 SKIL SRPK2 SSX2IP STK16 TAL1 UBE2I ZC3H15	7 interactors: DRG1 LMO1 LMO2 NFKB1 NFKBIA TCF3 TCF4
Entrez ID		4733	4066
HPRD ID		16034	01046
Ensembl ID		ENSG00000185721	ENSG00000104903
Uniprot IDs		Q9Y295	P12980
PDB IDs		2EKI
Enriched GO Terms of Interacting Partners?		Definitive Hemopoiesis Hemangioblast Cell Differentiation Nuclear Speck Organization Positive Regulation Of SUMO Transferase Activity Positive Regulation Of Chromatin Assembly Or Disassembly Anatomical Structure Formation Involved In Morphogenesis Basophil Differentiation Blood Vessel Development Vasculature Development	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cholesterol Transport Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Wnt Signaling Pathway Regulation Of Macrophage Derived Foam Cell Differentiation Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Immune System Process Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Negative Regulation Of Transcription, DNA-templated TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Somatic Stem Cell Maintenance RNA Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Type I Interferon Production Regulation Of RNA Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Response To Organic Substance Regulation Of RNA Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Response To Bacterium Regulation Of Immune System Process Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		carrying cc cd36 cg colon crc dscr1 dscr1rs6517239 endpoint generating genotype germline interesting japanese lep nfkb ngal norris obesity polymorphisms ppar pparrs1801282 probability recurrence regia se sided stronger univariate	alter box canntg consensus cos discrimination e12 e2a exclusively flanking helix hlh homology influenced initially lymphoblastic mitogen motif oncoprotein positioned residue ser122 ser172 serine sharing subcellular tal1 termed unaffected
Tagcloud (Difference) ?		carrying cc cd36 cg colon crc dscr1 dscr1rs6517239 endpoint generating genotype germline interesting japanese lep nfkb ngal norris obesity polymorphisms ppar pparrs1801282 probability recurrence regia se sided stronger univariate	alter box canntg consensus cos discrimination e12 e2a exclusively flanking helix hlh homology influenced initially lymphoblastic mitogen motif oncoprotein positioned residue ser122 ser172 serine sharing subcellular tal1 termed unaffected
Tagcloud (Intersection) ?