NUBP1 and NDN

Number of citations of the paper that reports this interaction (PubMedID 10915798)
0

Data Source:
HPRD (two hybrid)

		NUBP1	NDN
Description		NUBP iron-sulfur cluster assembly factor 1, cytosolic	necdin, MAGE family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Cell Projection	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Protein-containing Complex Cell Projection Perikaryon
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding ATP-dependent FeS Chaperone Activity	DNA Binding Protein Binding Gamma-tubulin Binding Promoter-specific Chromatin Binding
	Biological Process	Regulation Of Cell Growth Intracellular Iron Ion Homeostasis Negative Regulation Of Centrosome Duplication Iron-sulfur Cluster Assembly Cell Projection Organization Centrosome Localization Protein Localization To Cell Cortex	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Respiratory System Process Regulation Of DNA-templated Transcription Axonogenesis Axonal Fasciculation Central Nervous System Development Respiratory Gaseous Exchange By Respiratory System Glial Cell Migration Post-embryonic Development Sensory Perception Of Pain Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Neuron Development Axon Extension Multicellular Organismal-level Homeostasis Genomic Imprinting
Pathways		Cytosolic iron-sulfur cluster assembly	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases			Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321)	Body size at age 10 ( 32376654) Depressive symptoms (SSRI exposure interaction) ( 25649181) HDL cholesterol levels ( 32203549) Parkinson's disease (age of onset) ( 33884653) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		3 interacting genes: NDN SPRY2 TENM1	47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PALS2 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		4682	4692
HPRD ID		02611	03667
Ensembl ID		ENSG00000103274	ENSG00000182636
Uniprot IDs		P53384	Q99608 X5D982
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Neuron Development Developmental Growth Involved In Morphogenesis Cell Projection System Development Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ubiquitin-protein Transferase Inhibitor Activity Lung Growth Microtubule End Negative Regulation Of Lens Fiber Cell Differentiation Ionotropic Glutamate Receptor Complex Positive Regulation Of Phosphate Metabolic Process Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Respiratory System Development Developmental Growth Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium Dendritic Spine Membrane Neurotrophin TRK Receptor Signaling Pathway Regulation Of Phosphorylation Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Short-term Neuronal Synaptic Plasticity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Axis Elongation Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Sensory Perception Axonal Fasciculation Neuron Projection Fasciculation Genomic Imprinting Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Epigenetic Programming Of Gene Expression Neurotrophin Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Glial Cell Migration Respiratory System Process Gamma-tubulin Binding Positive Regulation Of MAP Kinase Activity Regulation Of Transcription By RNA Polymerase III Regulation Of Phosphorus Metabolic Process Regulation Of Protein Modification Process Positive Regulation Of Filopodium Assembly Regulation Of MAPK Cascade	Cis-regulatory Region Sequence-specific DNA Binding Axo-dendritic Transport Circadian Rhythm Transport Along Microtubule Cellular Response To Hypoxia Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Neuron Apoptotic Process Cytoskeleton-dependent Intracellular Transport Axon Cytoplasm Microtubule-based Transport Axonal Transport Circadian Regulation Of Gene Expression Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cellular Response To Insulin Stimulus Cytoplasm Cellular Response To Decreased Oxygen Levels DNA-binding Transcription Activator Activity Promoter-specific Chromatin Binding Embryonic Placenta Development Cellular Homeostasis Regulation Of MiRNA Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Rhythmic Process Cellular Response To Oxygen Levels Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Metabolic Process Intracellular Chemical Homeostasis Organelle Transport Along Microtubule Intracellular Glucose Homeostasis Regulation Of Fibroblast Proliferation Positive Regulation Of Biosynthetic Process Stress-induced Premature Senescence Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex MRNA Metabolic Process PML Body Anterograde Axonal Transport Nuclear Receptor Binding Connective Tissue Replacement Microtubule-based Process Intracellular Oxygen Homeostasis Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Gene Expression Protein Domain Specific Binding
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