CDC42BPA and LIMK2

Number of citations of the paper that reports this interaction (PMID 11340065)
14

Data Source:
HPRD (in vitro)

		CDC42BPA	LIMK2
Gene Name		CDC42 binding protein kinase alpha (DMPK-like)	LIM domain kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cell-cell Junction Cell Leading Edge Actomyosin Extracellular Vesicular Exosome	Nucleus Cytoplasm Cis-Golgi Network
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding Identical Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Protein Heterodimerization Activity
	Biological Process	Microtubule Cytoskeleton Organization Protein Phosphorylation Nuclear Migration Cell Migration Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction Regulation Of Catalytic Activity	Protein Phosphorylation Spermatogenesis Phosphorylation
Pathways			EPHB-mediated forward signaling Axon guidance Semaphorin interactions EPH-Ephrin signaling Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS			Paclitaxel-induced neuropathy ( 23776197) Type 2 diabetes nephropathy ( 21150874)
Protein-Protein Interactions		6 interactors: CDC42 LIMK1 LIMK2 MYL2 MYL9 PPP1R12C	9 interactors: CDC42BPA CFL1 GSN HIPK3 HIST1H1A LIMK1 MBP PARD3 ROCK1
Entrez ID		8476	3985
HPRD ID		04562	03585
Ensembl ID		ENSG00000143776	ENSG00000182541
Uniprot IDs		F5H5N0 Q5VT25	E7EUC1 P53671
PDB IDs			1X6A
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Axon Guidance Heart Contraction Movement Of Cell Or Subcellular Component Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Actin Cytoskeleton Organization Cell Development Neuron Projection Morphogenesis Actin Filament-based Process Muscle Cell Fate Specification Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Muscle Contraction Cell Projection Morphogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Actin Filament Branching Submandibular Salivary Gland Formation Neuron Development Cardiac Muscle Tissue Development Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Muscle Contraction Cell Morphogenesis Neuron Differentiation Cytoskeleton Organization Cell Projection Organization Establishment Of Golgi Localization Phagocytosis Muscle System Process Fc Receptor Signaling Pathway Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Cell Projection Organization Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Fate Commitment Blood Circulation Positive Regulation Of Cellular Component Biogenesis Striated Muscle Tissue Development Neuron Fate Determination	Actin Filament-based Process Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin Cytoskeleton Organization Rho Protein Signal Transduction Apical Constriction Ephrin Receptor Signaling Pathway Regulation Of Actin Cytoskeleton Organization Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Cell Morphogenesis Organelle Organization Regulation Of Cytoskeleton Organization Axonogenesis Cell Projection Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Locomotion Positive Regulation Of Cytoskeleton Organization Nervous System Development Protein Phosphorylation Neuron Projection Morphogenesis Ras Protein Signal Transduction Cell Morphogenesis Involved In Differentiation Movement Of Cell Or Subcellular Component Actin-mediated Cell Contraction Generation Of Neurons Neuron Projection Development Cell Migration Epithelial Cell Morphogenesis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Regulation Of Organelle Organization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Filament-based Movement Cell Development Regulation Of Stress Fiber Assembly Response To External Stimulus Regulation Of Actin Filament Depolymerization Phosphorylation Neuron Development Intracellular Signal Transduction Regulation Of Neuron Projection Development Regulation Of Cellular Component Organization Axon Guidance Execution Phase Of Apoptosis Positive Regulation Of Organelle Organization
Tagcloud ?			aberrant cdk4 cofilin cyclin d1 death downregulation drp1 dynamic effectors epilepticus fission interacting kip1 mediators necrotic neuronal p27 programmed rescue rho rock se subsequently turn unsuspected upregulated vulnerable
Tagcloud (Difference) ?			aberrant cdk4 cofilin cyclin d1 death downregulation drp1 dynamic effectors epilepticus fission interacting kip1 mediators necrotic neuronal p27 programmed rescue rho rock se subsequently turn unsuspected upregulated vulnerable
Tagcloud (Intersection) ?