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CDC42BPA
Description
CDC42 binding protein kinase alpha
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Cell-cell Junction
Lamellipodium
Cell Leading Edge
Actomyosin
Cell Projection
Extracellular Exosome
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Kinase Activity
Transferase Activity
Identical Protein Binding
Metal Ion Binding
Protein Serine Kinase Activity
Biological Process
Protein Phosphorylation
Cytoskeleton Organization
Cell Migration
Actin Cytoskeleton Organization
Actomyosin Structure Organization
Pathways
CDC42 GTPase cycle
RAC1 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
Drugs
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Blood urea nitrogen levels (
31152163
)
Cardiovascular death or myocardial infarction in response to clopidogrel treatment (
32472697
)
Diastolic blood pressure (
28135244
)
Low density lipoprotein cholesterol levels (
33339817
)
Macular thickness (
30535121
)
Mercury levels (
26025379
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
)
Optic cup area (
25631615
31798171
)
Optic disc area (
25631615
31798171
28073927
)
Optic disc size (
31809533
)
SAPHO syndrome (
33816493
)
Smoking initiation (
33082346
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Waist circumference adjusted for body mass index (
34021172
)
White blood cell count (
32888494
)
Interacting Genes
10 interacting genes:
CDC42
LIMK1
LIMK2
MYL2
MYL9
PPM1A
PPP1R12C
SNAPIN
TAF1
USP7
Entrez ID
8476
HPRD ID
04562
Ensembl ID
ENSG00000143776
Uniprot IDs
A0A0A0MRJ0
A0A0A0MRJ1
Q5VT25
PDB IDs
Enriched GO Terms of Interacting Partners
?
Actin Filament-based Process
Actin Cytoskeleton Organization
Supramolecular Fiber Organization
Myosin Heavy Chain Binding
Actomyosin Structure Organization
Heart Contraction
Cytoskeleton
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Organelle Organization
Cytoskeleton Organization
Myofibril Assembly
Heart Process
Structural Constituent Of Muscle
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Positive Regulation Of Stress Fiber Assembly
Actin Filament Organization
Establishment Of Organelle Localization
Regulation Of Cell Projection Organization
Myosin Complex
Myofibril
Regulation Of Intracellular Transport
Positive Regulation Of Actin Filament Bundle Assembly
Actin Filament Bundle Assembly
Muscle Cell Fate Specification
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Androgen Receptor Signaling Pathway
Positive Regulation Of Late Endosome To Lysosome Transport
Actin Filament Bundle Organization
P53 Binding
Cellular Component Assembly
Protein Serine Kinase Activity
Protein Phosphorylation
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Cellular Component Organization
GBD Domain Binding
Storage Vacuole
Organelle Transport Along Microtubule
Negative Regulation Of Protein Autoubiquitination
Stress Fiber
Phosphorylation
Protein Modification Process
Regulation Of Cell Growth
Regulation Of Stress Fiber Assembly
Protein Serine/threonine Kinase Activity
Developmental Process
Endothelin Receptor Signaling Pathway Involved In Heart Process
Establishment Of Vesicle Localization
Symbiont-mediated Disruption Of Host Cell PML Body
Organelle Localization
Tagcloud
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