CDC34 and FBXO32

Number of citations of the paper that reports this interaction (PMID 19073596)
12

Data Source:
BioGRID (pull down)

		CDC34	FBXO32
Gene Name		cell division cycle 34	F-box protein 32
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleolus Z Disc
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly	Response To Denervation Involved In Regulation Of Muscle Adaptation Protein Ubiquitination Cellular Response To Dexamethasone Stimulus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: ANAPC11 ATF5 BTRC CCNE1 CDK9 CDKN1B CREM CSNK2B CUL1 CUL2 CUL3 FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCH1 MARCH2 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARG RBX1 RELA RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TRIM21 TRIM28 UBA1 UBB VHL WWP2 ZFAND6 ZNRF1	6 interactors: CDC34 EIF3A EIF3F MLH1 SKP1 UBE2D3
Entrez ID		997	114907
HPRD ID		00306	05966
Ensembl ID		ENSG00000099804	ENSG00000156804
Uniprot IDs		P49427	I6L984 Q0VAQ6 Q498Y9 Q969P5
PDB IDs		2OB4 3RZ3
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Proteolysis Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Viral Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Protein Monoubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Catabolic Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Gene Expression Cell Cycle Phase Transition Cellular Response To Oxygen Levels Cellular Response To Stimulus Regulation Of Protein Catabolic Process Response To Stimulus Cellular Response To Stress Regulation Of Protein Stability Notch Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Cycle Negative Regulation Of RNA Biosynthetic Process Cell Cycle Regulation Of Transcription, DNA-templated Apoptotic Process Regulation Of Nucleic Acid-templated Transcription G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Programmed Cell Death Regulation Of Protein Metabolic Process	Formation Of Translation Preinitiation Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Protein K48-linked Ubiquitination Protein Monoubiquitination Regulation Of Translational Initiation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteolysis Cellular Protein Catabolic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Protein Ubiquitination Protein Catabolic Process Protein Modification By Small Protein Conjugation Cellular Macromolecular Complex Assembly Catabolic Process Negative Regulation Of Mitotic Recombination G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Ribonucleoprotein Complex Assembly Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Cellular Protein Metabolic Process Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Cell Cycle Process DNA Metabolic Process Positive Regulation Of Inclusion Body Assembly Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of CAMP-mediated Signaling Regulation Of Translation Spindle Midzone Assembly Mature Ribosome Assembly Ribosomal Subunit Export From Nucleus Cytoplasmic Translational Initiation Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Resolution Of Meiotic Recombination Intermediates Histone H2A Monoubiquitination Cell Cycle Protein Metabolic Process Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Histone H2A Ubiquitination Cytoplasmic Translation Cellular Protein Modification Process
Tagcloud ?		apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin	ameliorated aquafeeds catabolic daidzein determines equol extend fishmeal genistein glycitein greatest ici legumes mitogenic mum mykiss myocyte nutrient oncorhynchus phytoestrogen phytoestrogens rainbow replacements salmonid soy soybeans trout turnover warrant
Tagcloud (Difference) ?		apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin	ameliorated aquafeeds catabolic daidzein determines equol extend fishmeal genistein glycitein greatest ici legumes mitogenic mum mykiss myocyte nutrient oncorhynchus phytoestrogen phytoestrogens rainbow replacements salmonid soy soybeans trout turnover warrant
Tagcloud (Intersection) ?