KLHL41 and NRAP

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, two hybrid)

		KLHL41	NRAP
Description		kelch like family member 41	nebulin related anchoring protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Membrane Sarcoplasmic Reticulum Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane Cell Projection	Cytoplasm Fascia Adherens Muscle Tendon Junction Myofibril Z Disc
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Actin Binding Protein Binding Vinculin Binding Metal Ion Binding Actin Filament Binding Muscle Alpha-actinin Binding
	Biological Process	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Skeletal Muscle Cell Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Myoblast Differentiation Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation	Cardiac Muscle Thin Filament Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Plasma factor VII activating protease levels ( 30070759) QT interval ( 29874175)
Interacting Genes		9 interacting genes: IFRD1 MYBPC1 NRAP POMP RBM4 RCHY1 SLC2A4 SPMIP2 TCAP	8 interacting genes: ACTA1 ACTB ACTN3 KLHL41 PRKAA2 TLN1 TRIM63 VCL
Entrez ID		10324	4892
HPRD ID		07610	04189
Ensembl ID		ENSG00000239474	ENSG00000197893
Uniprot IDs		O60662	A0A0A0MRM2 Q86VF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Titin Binding	Muscle System Process Actin Cytoskeleton Brush Border Cell Junction Assembly Platelet Aggregation Homotypic Cell-cell Adhesion Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Actin Filament Muscle Atrophy Regulation Of Purine Nucleotide Metabolic Process Structural Constituent Of Cytoskeleton Actin Cytoskeleton Organization Actin Filament-based Process Cell-cell Junction Assembly Adherens Junction Assembly Focal Adhesion Regulation Of Generation Of Precursor Metabolites And Energy Pseudopodium Cell Junction Organization Negative Regulation Of Glycolytic Process Negative Regulation Of ATP Metabolic Process M Band Cell-cell Junction Organization Adherens Junction Muscle Contraction Maintenance Of Blood-brain Barrier Cell-substrate Junction Assembly Cell-substrate Junction Organization Cytoskeleton Adherens Junction Organization Sarcomere Regulation Of Small Molecule Metabolic Process Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Focal Adhesion Assembly Inner Dense Plaque Of Desmosome Podosome Ring Outer Dense Plaque Of Desmosome Regulation Of Myoblast Differentiation Actin Binding Regulation Of Cell-substrate Junction Organization Cytoskeleton Organization Cytoplasm Muscle Cell Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?