KRTAP5-2 and LCE3E

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		KRTAP5-2	LCE3E
Name		keratin associated protein 5-2	late cornified envelope 3E
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	None
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	None	Epidermis Development Keratinization
Pathways		Keratinization	Formation of the cornified envelope
Drugs		Beta-D-Glucose Pidolic acid	None
GWAS		No GWAS studies recorded	Allergic disease (asthma, hay fever or eczema) ( 29785011 ) Asthma ( 31619474 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Atopic dermatitis ( 26482879 ) Common traits (Other) ( 20585627 ) Inflammatory skin disease ( 25574825 ) Plantar warts ( 28928442 ) Psoriasis ( 25854761 )
Interacting Genes		61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I	59 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP2 GRN GSC2 HOXA1 KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE2A MACO1 MDFI NBPF19 NOTCH2NLA NXF1 PLSCR2 RGS17 RGS20 SPRY1 SPRY2 SPRY3 TRIM42 VWC2
Entrez ID		440021	353145
HPRD ID		17249	13975
Ensembl ID		ENSG00000205867	ENSG00000185966
Uniprot IDs		Q701N4	Q5T5B0
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding	Intermediate Filament Keratin Filament Hair Cycle Cytosol Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Epidermis Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Lens Fiber Cell Differentiation Protein Binding Regulation Of Ras Protein Signal Transduction Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Branch Elongation Of An Epithelium Structural Constituent Of Skin Epidermis Negative Regulation Of Small GTPase Mediated Signal Transduction