KRTAP5-2 and DLGAP3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		KRTAP5-2	DLGAP3
Name		keratin associated protein 5-2	DLG associated protein 3
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Plasma Membrane Postsynaptic Density Membrane Neuromuscular Junction Synapse Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding	Amyloid-beta Binding Protein Binding Molecular Adaptor Activity
	Biological Process	None	Signaling Modulation Of Chemical Synaptic Transmission Modification Of Postsynaptic Structure
Pathways		Keratinization	Neurexins and neuroligins Neurexins and neuroligins
Drugs		Beta-D-Glucose Pidolic acid	None
GWAS		No GWAS studies recorded	Glomerular filtration rate in chronic kidney disease ( 26420894 ) Nicotine dependence ( 28440896 )
Interacting Genes		61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I	15 interacting genes: DLG1 DLG2 DLG3 DLG4 DLGAP1 GOLGA2 KANK2 KRTAP1-3 KRTAP5-2 MAGEA6 MAGI2 PTK2 PTK2B SHANK2 SHANK3
Entrez ID		440021	58512
HPRD ID		17249	18935
Ensembl ID		ENSG00000205867	ENSG00000116544
Uniprot IDs		Q701N4	O95886
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding	Ionotropic Glutamate Receptor Binding Receptor Clustering Postsynaptic Density Neuron Projection Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Membrane Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Neuromuscular Junction Protein Localization To Cell Junction Vocalization Behavior Protein Kinase Binding Kinase Binding Postsynaptic Density Membrane Beta-1 Adrenergic Receptor Binding Positive Regulation Of Excitatory Postsynaptic Potential Localization Within Membrane Synaptic Receptor Adaptor Activity Chemical Synaptic Transmission Synapse Positive Regulation Of Synaptic Transmission Trans-synaptic Signaling AMPA Glutamate Receptor Clustering Synaptic Signaling Modulation Of Excitatory Postsynaptic Potential Phosphatase Binding Social Behavior Adherens Junction Neuron Spine Signal Complex Assembly Regulation Of Synaptic Plasticity GMP Kinase Activity GDP Metabolic Process Cell Projection Juxtaparanode Region Of Axon Modulation Of Chemical Synaptic Transmission Regulation Of Cell Morphogenesis Regulation Of Cellular Component Size Neurotransmitter-gated Ion Channel Clustering Regulation Of Cytoskeleton Organization Cellular Response To Potassium Ion Regulation Of Actin Filament Organization Glutamatergic Synapse Regulation Of Biological Quality Nervous System Development Dendritic Spine Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction