KRTAP5-2 and FAM76B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP5-2	FAM76B
Description		keratin associated protein 5-2	family with sequence similarity 76 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleus Nuclear Speck
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process		Negative Regulation Of Macrophage Activation Negative Regulation Of Protein Export From Nucleus MRNA Stabilization Negative Regulation Of Inflammatory Response
Pathways		Keratinization
Drugs		Beta-D-Glucose Pidolic acid
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Chronotype ( 30696823) Diastolic blood pressure ( 27841878) Feeling worry ( 29500382) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Keratoconus ( 33649486) Macular thickness ( 30535121) Monocyte count ( 29403010) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Refractive error ( 32231278) Sun-seeking behavior ( 32920024) Triglyceride levels x loop diuretics use interaction ( 31806883) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) White blood cell count ( 29403010)
Interacting Genes		61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I	22 interacting genes: CEBPA CNKSR3 GRN KRTAP1-1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-9 KRTAP9-2 PRMT5 SRPK1 SRPK2
Entrez ID		440021	143684
HPRD ID		17249	11333
Ensembl ID		ENSG00000205867	ENSG00000077458
Uniprot IDs		Q701N4	F5GX09 Q5HYJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding	Intermediate Filament Keratin Filament Hair Cycle Cytosol Regulation Of MRNA Splicing, Via Spliceosome
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