KRTAP5-2 and TACSTD2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		KRTAP5-2	TACSTD2
Name		keratin associated protein 5-2	tumor associated calcium signal transducer 2
Structure		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Space Nucleus Cytosol Plasma Membrane Basal Plasma Membrane Membrane Lateral Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	None	Visual Perception Negative Regulation Of Epithelial Cell Migration Regulation Of Epithelial Cell Proliferation Negative Regulation Of Stress Fiber Assembly Ureteric Bud Morphogenesis Negative Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Ruffle Assembly Negative Regulation Of Cell Motility Positive Regulation Of Stem Cell Differentiation
Pathways		Keratinization	None
Drugs		Beta-D-Glucose Pidolic acid	Sacituzumab govitecan
Diseases		None	Gelatinous drop-like corneal dystrophy (GDCD); Subepithelial amyloidosis; Primary familial amyloidosis
GWAS		No GWAS studies recorded	Nickel levels ( 26025379 )
Interacting Genes		61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I	3 interacting genes: KRTAP1-3 KRTAP10-8 KRTAP5-2
Entrez ID		440021	4070
HPRD ID		17249	00672
Ensembl ID		ENSG00000205867	ENSG00000184292
Uniprot IDs		Q701N4	P09758
PDB IDs		Not available	2MAE 2MVK 2MVL 7E5M 7E5N 7PEE
GO Terms Enriched among Interactors		Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding	Intermediate Filament Keratin Filament Leading Edge Cell Differentiation Cellular Response To Anisomycin Response To Anisomycin Release From Viral Latency Transcription Factor AP-1 Complex