ASL and QARS

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASL	QARS
Gene Name		argininosuccinate lyase	glutaminyl-tRNA synthetase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Cytoplasm Mitochondrial Matrix Cytosol
	Molecular Function	Argininosuccinate Lyase Activity	Glutamine-tRNA Ligase Activity Protein Binding ATP Binding
	Biological Process	Urea Cycle Internal Protein Amino Acid Acetylation Arginine Catabolic Process Cellular Nitrogen Compound Metabolic Process Arginine Biosynthetic Process Via Ornithine Small Molecule Metabolic Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Brain Development Gene Expression
Pathways		Urea cycle Metabolism of amino acids and derivatives	Cytosolic tRNA aminoacylation tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs		L-Arginine Argininosuccinate 2-(N-Morpholino)-Ethanesulfonic Acid
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CSNK2A2 FBP1 HMOX1 OVGP1 QARS WDYHV1	37 interactors: AES ANXA7 APP ASL CDK4 CDKN1A CLTC CPNE3 DPPA4 DTX2 DUSP11 FAM118B GADD45A GSK3B H2AFX IRF1 KCNE3 KLC3 LAMTOR3 LZTS2 MAP3K5 PIK3R3 PIN1 PRRC2A RARS RNF11 SMAD9 SMN1 STK3 TCF12 TK1 TRAF2 TRAF4 TRIP13 TSC22D1 TTR VPS37B
Entrez ID		435	5859
HPRD ID		01948	07223
Ensembl ID		ENSG00000126522	ENSG00000172053
Uniprot IDs		P04424	B4DWJ2 B7Z840 P47897
PDB IDs		1AOS 1K62
Enriched GO Terms of Interacting Partners?		Glutaminyl-tRNA Aminoacylation Cellular Response To Metal Ion Prolyl-tRNA Aminoacylation Cellular Response To Inorganic Substance Smooth Muscle Hyperplasia Glutamyl-tRNA Aminoacylation Negative Regulation Of Mast Cell Cytokine Production Cellular Response To Magnesium Ion Negative Regulation Of Binding Of Sperm To Zona Pellucida Smooth Muscle Adaptation Negative Regulation Of Mast Cell Degranulation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Protein Complex Assembly Negative Regulation Of Mast Cell Activation Involved In Immune Response Heme Catabolic Process Protein Homooligomerization Wound Healing Involved In Inflammatory Response Chitin Catabolic Process Chitin Metabolic Process Heme Oxidation Negative Regulation Of Glycolytic Process Cellular Response To Arsenic-containing Substance Response To Metal Ion Negative Regulation Of Mast Cell Activation Positive Regulation Of Chemokine Biosynthetic Process Cellular Response To Iron Ion Cellular Response To Cadmium Ion Endothelial Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Protein Oligomerization Fructose Metabolic Process Response To Magnesium Ion Fructose 6-phosphate Metabolic Process Response To Inorganic Substance Negative Regulation Of Leukocyte Migration Low-density Lipoprotein Particle Clearance Regulation Of Mast Cell Degranulation Response To Arsenic-containing Substance Regulation Of Glycolytic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Vasodilation Cellular Component Assembly Response To Iron Ion Negative Regulation Of Muscle Cell Apoptotic Process Regulation Of Mast Cell Activation Plasma Lipoprotein Particle Clearance Negative Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Response To Nicotine Mitotic Spindle Checkpoint	Regulation Of Protein Binding Regulation Of Kinase Activity Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Regulation Of Binding Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Binding Regulation Of JNK Cascade Response To Inorganic Substance Regulation Of Phosphorus Metabolic Process Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Apoptotic Process Programmed Cell Death Positive Regulation Of Transferase Activity Cell Cycle Process Metabolic Process Cell Death Death Cell Cycle Cellular Protein Modification Process Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Regulation Of Apoptotic Process Positive Regulation Of Binding Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Protein Homodimerization Activity Regulation Of Metabolic Process Response To Stimulus Innate Immune Response
Tagcloud ?		agnosia argue auditory coded comprehension compromised disruptions english grammar grew impoverished input kleffner landau language lexical linguistic lks manually phonological phonology pitch sign signed speaking spoken syntactic verbal written	aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical
Tagcloud (Difference) ?		agnosia argue auditory coded comprehension compromised disruptions english grammar grew impoverished input kleffner landau language lexical linguistic lks manually phonological phonology pitch sign signed speaking spoken syntactic verbal written	aars acylating aminoacyl aminoars aminoarss bodies canonical dorsal drg functions ganglia glutaminyl horn injured kars lysyl nerve pharmaceutical possibility powerful primers root satellite sensory spinal synthetase synthetases trna typical
Tagcloud (Intersection) ?