MLLT1 and HIST1H1B

Number of citations of the paper that reports this interaction (PMID 15856011)
23

Data Source:
BioGRID (pull down)

		MLLT1	HIST1H1B
Gene Name		myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	histone cluster 1, H1b
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Transcription Elongation Factor Complex	Nucleosome Nuclear Chromatin Nuclear Heterochromatin Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding	Chromatin DNA Binding Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Assembly Positive Regulation Of Cell Growth Protein Stabilization Positive Regulation Of Histone H3-K9 Methylation Establishment Of Protein Localization To Chromatin
Pathways			DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AFF1 AFF4 ARID1A CBX8 HIST1H1B HIST3H3 MLLT10 PAF1 WDR5	26 interactors: CBX5 CCNA1 CCNA2 CCNB1 CCNE1 CDK1 CDK2 CDK5 CDKN1A CDKN1B EHMT2 IRAK4 KAT2A KAT2B L3MBTL1 LOX MELK MLLT1 NSD1 PRKCA PRKCB PRKCD PRKCZ RPS6KA5 SERPINH1 SIRT1
Entrez ID		4298	3009
HPRD ID		15933	00821
Ensembl ID			ENSG00000184357
Uniprot IDs		Q03111	P16401
PDB IDs			2FE2 2RHI
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Histone Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Modification RNA Metabolic Process Nucleosome Mobilization Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Optic Cup Formation Involved In Camera-type Eye Development Regulation Of Protein Stability Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Protein Localization To Chromatin Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Optic Cup Morphogenesis Involved In Camera-type Eye Development Glucocorticoid Receptor Signaling Pathway Histone H2B Ubiquitination Biosynthetic Process	Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Histone Modification Peptidyl-amino Acid Modification Chromatin Modification Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Cell Cycle Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Chromatin Organization Histone Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Modification Process Regulation Of Mitotic Cell Cycle Cell Cycle Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Chromosome Organization Regulation Of Catalytic Activity Negative Regulation Of Phosphorylation Protein Phosphorylation G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Response To Stress Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Metabolic Process Protein Metabolic Process Response To Wounding Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Protein Metabolic Process Peptidyl-threonine Phosphorylation Peptidyl-serine Phosphorylation Regulation Of RNA Metabolic Process Negative Regulation Of Protein Kinase Activity Regulation Of Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Kinase Activity Positive Regulation Of Cell Proliferation Negative Regulation Of Protein Serine/threonine Kinase Activity Wound Healing
Tagcloud ?		abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt3 mllt4 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Difference) ?		abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt3 mllt4 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Intersection) ?