BTNL9 and UPK2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTNL9	UPK2
Description		butyrophilin like 9	uroplakin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway	Epithelial Cell Differentiation
Pathways		Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Asthma ( 31959851)
Interacting Genes		16 interacting genes: ADAM33 ADIPOQ CXCL9 CYB5B EDDM3A GIMAP5 JAGN1 NINJ2 PLPP6 RPRM SLC38A7 SLC61A1 SMIM3 SYS1 TNF UPK2	36 interacting genes: ADGRG3 AMIGO1 ASGR2 ATP6AP2 BSCL2 BTNL9 C3orf52 CD74 CLDN7 CLEC17A CLEC7A CYB5R3 FCGR1A FCGR2A FCGRT FKBP7 FNDC9 GPA33 HPN ITM2C KASH5 KIR2DL3 KIR3DL3 LIME1 PLP1 RNF170 SLC18A1 SLC22A23 SMAGP STOML3 TMEM106C TMPRSS2 TNFSF11 TNFSF14 UPK1A ZNRF4
Entrez ID		153579	7379
HPRD ID		12550	10295
Ensembl ID		ENSG00000165810	ENSG00000110375
Uniprot IDs		A0A1S5UZ21 Q6UXG8 Q8N324	O00526
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Cytokine-mediated Signaling Pathway Membrane Negative Regulation Of Bile Acid Secretion Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Protein Localization To Plasma Membrane Response To Gram-negative Bacterium Negative Regulation Of Secretion Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Negative Regulation Of Blood Pressure Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Sperm Displacement L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Cytokine Activity Leukocyte Migration Neutrophil Migration Regulation Of Hormone Secretion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Protein Localization To Cell Periphery Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Regulation Of D-glucose Import Positive Regulation Of Vitamin D Biosynthetic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Detection Of Oxidative Stress Negative Regulation Of Hormone Secretion Positive Regulation Of Chemokine Production Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Response To Other Organism	Membrane Plasma Membrane Immune Response-regulating Signaling Pathway External Side Of Plasma Membrane Immune System Process IgG Binding Immune Response Regulation Of Immune Response Regulation Of Immune System Process IgG Receptor Activity Regulation Of Non-canonical NF-kappaB Signal Transduction Pattern Recognition Receptor Activity Immunoglobulin Mediated Immune Response Fucose Binding B Cell Mediated Immunity Antibody-dependent Cellular Cytotoxicity Protein Binding Positive Regulation Of Immune System Process Endoplasmic Reticulum Endoplasmic Reticulum Membrane Hypersensitivity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Phagocytosis, Recognition Positive Regulation Of Immune Response Positive Regulation Of Viral Entry Into Host Cell Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Phagocytosis Acute Inflammatory Response To Antigenic Stimulus Immune Response-activating Signaling Pathway Regulation Of Viral Entry Into Host Cell D-mannose Binding Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Viral Life Cycle Regulation Of Phagocytosis Positive Regulation Of Acute Inflammatory Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Tumor Necrosis Factor Production MHC Class II Protein Binding, Via Antigen Binding Groove NOS2-CD74 Complex Macrophage Migration Inhibitory Factor Signaling Pathway Lymphocyte Mediated Immunity Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production High-affinity IgG Receptor Activity IgG Immunoglobulin Transcytosis In Epithelial Cells Mediated By FcRn Immunoglobulin Receptor Tumor Necrosis Factor Receptor Binding Eye Pigmentation Activation Of Immune Response Detection Of Yeast Detection Of Molecule Of Fungal Origin
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