MID1 and UBTD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MID1	UBTD1
Gene Name		midline 1	ubiquitin domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule
	Molecular Function	Microtubule Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding
	Biological Process	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Metabolic Process Cytokine-mediated Signaling Pathway Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: BYSL DYRK4 EHHADH FKBP1A GMCL1 HTT IGBP1 MEOX1 MID1IP1 MID2 OTUB2 PKN1 PPP2CA PPP2CB PPP2R4 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1	13 interactors: BCOR CD1A FZD5 KIAA2026 MID1 MID2 MRFAP1L1 PFKM RANBP2 RNF10 TEAD1 TRIM39 UBE2D4
Entrez ID		4281	80019
HPRD ID		02047	08568
Ensembl ID		ENSG00000101871	ENSG00000165886
Uniprot IDs		O15344	Q9HAC8
PDB IDs		2DQ5 2FFW 2JUN
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Cellular Protein Modification Process Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Protein K63-linked Ubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Cellular Metabolic Process Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Proteasomal Protein Catabolic Process Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Innate Immune Response Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Cellular Response To Stress Proteolysis Positive Regulation Of Protein Modification Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Innate Immune Response Regulation Of Dephosphorylation Protein Monoubiquitination Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Dephosphorylation ISG15-protein Conjugation Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Cellular Response To Organic Substance Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Transferase Activity Regulation Of Catalytic Activity	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Localization To Microtubule Protein Localization To Cytoskeleton Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Tooth Mineralization Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Pattern Specification Process Axis Specification Depurination Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Protein Localization To Organelle Cellular Protein Modification Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Signal Transduction Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Specification Of Axis Polarity Negative Regulation Of Odontogenesis Negative Regulation Of Glucokinase Activity Positive Regulation Of Stem Cell Maintenance DNA Dealkylation Involved In DNA Repair Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Histone H3-K4 Methylation Base-excision Repair, AP Site Formation Chorionic Trophoblast Cell Differentiation Protein K6-linked Ubiquitination Glucose Homeostasis Chorion Development Pathogenesis Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Myelination Regulation Of Tight Junction Assembly Negative Regulation Of Glial Cell Proliferation Post-embryonic Camera-type Eye Development Fructose 6-phosphate Metabolic Process Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Intracellular Signal Transduction Histone H2A Monoubiquitination Regulation Of Metabolic Process Lateral Mesoderm Development Cardiovascular System Development Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination
Tagcloud ?		adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably	attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Difference) ?		adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably	attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Intersection) ?