MID1 and IGBP1

Number of citations of the paper that reports this interaction (PMID 11371618)
16

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo)

		MID1	IGBP1
Gene Name		midline 1	immunoglobulin (CD79A) binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule	Cytoplasm Microtubule
	Molecular Function	Microtubule Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	Protein Binding Protein Phosphatase Type 2A Regulator Activity Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Binding
	Biological Process	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Metabolic Process Cytokine-mediated Signaling Pathway Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Positive Regulation Of Dephosphorylation Negative Regulation Of Protein Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Microtubule-based Movement Response To Interleukin-1 Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: BYSL DYRK4 EHHADH FKBP1A GMCL1 HTT IGBP1 MEOX1 MID1IP1 MID2 OTUB2 PKN1 PPP2CA PPP2CB PPP2R4 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1	9 interactors: APP LINC01257 LOC81691 MID1 MID2 PPP2CA PPP4C PPP6C S100A13
Entrez ID		4281	3476
HPRD ID		02047	02140
Ensembl ID		ENSG00000101871	ENSG00000089289
Uniprot IDs		O15344	P78318
PDB IDs		2DQ5 2FFW 2JUN	4IYP
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Cellular Protein Modification Process Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Protein K63-linked Ubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Cellular Metabolic Process Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Proteasomal Protein Catabolic Process Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Innate Immune Response Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Cellular Response To Stress Proteolysis Positive Regulation Of Protein Modification Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Innate Immune Response Regulation Of Dephosphorylation Protein Monoubiquitination Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Dephosphorylation ISG15-protein Conjugation Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Cellular Response To Organic Substance Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Transferase Activity Regulation Of Catalytic Activity	Protein Localization To Microtubule Protein Localization To Cytoskeleton Interleukin-1 Alpha Secretion Dephosphorylation Immune Response Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Regulation Of Signal Transduction Depurination Collateral Sprouting In Absence Of Injury Phosphate-containing Compound Metabolic Process Regulation Of Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Intracellular Signal Transduction Cellular Protein Modification Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Interleukin-1 Secretion Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition DNA Dealkylation Involved In DNA Repair Base-excision Repair, AP Site Formation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Dephosphorylation Neuron Remodeling Mitotic Nuclear Envelope Reassembly Immune System Process Protein Heterotrimerization Nuclear Envelope Reassembly Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Cell Development Cellular Localization Exocytosis Negative Regulation Of Viral Entry Into Host Cell Deoxyribose Phosphate Catabolic Process Cellular Copper Ion Homeostasis Positive Regulation Of Signal Transduction Negative Regulation Of Epithelial To Mesenchymal Transition Cellular Protein Metabolic Process Regulation Of Viral Entry Into Host Cell Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Phosphorylation Regulation Of Viral Release From Host Cell Negative Regulation Of JAK-STAT Cascade
Tagcloud ?		adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably
Tagcloud (Difference) ?		adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably
Tagcloud (Intersection) ?