DHX8 and PRPF38A

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		DHX8	PRPF38A
Gene Name		DEAH (Asp-Glu-Ala-His) box polypeptide 8	pre-mRNA processing factor 38A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Catalytic Step 2 Spliceosome	Nucleus Nuclear Membrane Precatalytic Spliceosome
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Identical Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing	MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: MFAP1 NKAP PRPF38A PRPF40A RBM7 RBMX2 SAP30BP SRPK1 SRPK2 THOC1 ZCCHC10	21 interactors: APP CHERP CLK2 CSNK2A1 DHX8 GTF3C1 JMJD6 MAPK6 POLA2 PPIG PRMT5 RBM39 RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRSF3 SRSF4 U2AF1 ZCCHC10
Entrez ID		1659	84950
HPRD ID		02672	10972
Ensembl ID		ENSG00000067596
Uniprot IDs		F5H658 Q14562	Q8NAV1
PDB IDs		2EQS 3I4U
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Positive Regulation Of Viral Genome Replication Gene Expression Negative Regulation Of Viral Genome Replication Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Viral Process Negative Regulation Of Isotype Switching To IgA Isotypes Nuclear Speck Organization Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Nitrogen Compound Metabolic Process Nucleus Organization Negative Regulation Of DNA Damage Checkpoint Regulation Of Viral Process Viral MRNA Export From Host Cell Nucleus Sperm Chromatin Condensation Regulation Of Cell Cycle Regulation Of DNA Damage Checkpoint Hematopoietic Stem Cell Proliferation Replication Fork Processing Granulocyte Differentiation Negative Regulation Of DNA Recombination Regulation Of Lymphocyte Activation	RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA 3'-end Processing Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Intracellular Transport Nucleocytoplasmic Transport Nuclear Transport Nuclear Export MRNA Transport RNA Transport RNA Localization Establishment Of Localization In Cell Cellular Metabolic Process Cytoplasmic Transport Transcription, DNA-templated RNA Biosynthetic Process Cellular Localization Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of Viral Genome Replication Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Phosphorylation Cellular Protein Modification Process Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of RNA Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process
Tagcloud ?		avenues bioinformatics bl canonical conferring disrupted dnaja1 galactosidase gtf2e1 gtf2e2 hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?		avenues bioinformatics bl canonical conferring disrupted dnaja1 galactosidase gtf2e1 gtf2e2 hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?