DHX8

Gene Name		DEAH (Asp-Glu-Ala-His) box polypeptide 8
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Catalytic Step 2 Spliceosome
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: MFAP1 NKAP PRPF38A PRPF40A RBM7 RBMX2 SAP30BP SRPK1 SRPK2 THOC1 ZCCHC10
Entrez ID		1659
HPRD ID		02672
Ensembl ID		ENSG00000067596
Uniprot IDs		F5H658 Q14562
PDB IDs		2EQS 3I4U
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Positive Regulation Of Viral Genome Replication Gene Expression Negative Regulation Of Viral Genome Replication Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Viral Process Negative Regulation Of Isotype Switching To IgA Isotypes Nuclear Speck Organization Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Nitrogen Compound Metabolic Process Nucleus Organization Negative Regulation Of DNA Damage Checkpoint Regulation Of Viral Process Viral MRNA Export From Host Cell Nucleus Sperm Chromatin Condensation Regulation Of Cell Cycle Regulation Of DNA Damage Checkpoint Hematopoietic Stem Cell Proliferation Replication Fork Processing Granulocyte Differentiation Negative Regulation Of DNA Recombination Regulation Of Lymphocyte Activation
Tagcloud ?		avenues bioinformatics bl canonical conferring disrupted dnaja1 galactosidase gtf2e1 gtf2e2 hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1