MBP and CTDSP1

Number of citations of the paper that reports this interaction (PMID 14743429)
3

Data Source:
HPRD (in vitro, in vivo)

		MBP	CTDSP1
Gene Name		myelin basic protein	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
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Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Internode Region Of Axon Neuronal Cell Body Compact Myelin	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Protease Binding Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding CTD Phosphatase Activity Metal Ion Binding
	Biological Process	Immune Response Synaptic Transmission Central Nervous System Development Aging Axon Ensheathment Response To Toxic Substance Substantia Nigra Development Response To Progesterone Response To Tumor Necrosis Factor Myelination Response To Mercury Ion Negative Regulation Of Axonogenesis Membrane Organization Response To Fatty Acid	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration (GA) ( 22705344)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		72 interactors: ABL1 APTX ATN1 ATXN1 BMP2K CCNC CCNH CCNT1 CDK1 CDK12 CDK5 CDK7 CDK8 CDK9 CLK1 CTDSP1 DYRK1B HIPK2 HLA-DRA IKBKE IRAK1 IRAK4 LIMK1 LIMK2 LRRK2 MAG MAP3K3 MAP3K5 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPKAPK5 MELK MICU2 MKNK1 MMP7 MNAT1 NEK9 PAK1 PKN1 PLP1 PPP2R5C PRKACA PRKCA PRKCB PRKCD PRKCI PRKCZ PRKDC PRMT1 PRMT5 RAN RPS6KA5 RTN4 SQSTM1 SRPK1 STK16 STK26 STK3 STK39 STK4 TBK1 TLK1 TLK2 TRAF6 TRPM7 TSSK6 ULK1	6 interactors: CDCA3 GTF2F1 LDB1 MBP POLR2A SNAI1
Entrez ID		4155	58190
HPRD ID		01158	05615
Ensembl ID		ENSG00000197971	ENSG00000144579
Uniprot IDs		P02686	Q9GZU7
PDB IDs		1BX2 1FV1 1HQR 1QCL 1YMM 1ZGL	1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL
Enriched GO Terms of Interacting Partners?		Protein Phosphorylation Phosphorylation Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Intracellular Signal Transduction Regulation Of Protein Phosphorylation Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Signal Transduction By Phosphorylation Protein Autophosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To Stress Regulation Of Protein Kinase Activity Peptidyl-threonine Phosphorylation Cellular Response To Growth Factor Stimulus Peptidyl-amino Acid Modification Regulation Of Protein Metabolic Process Response To Growth Factor Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway MAPK Cascade Cellular Response To Stress Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Signaling Neurotrophin TRK Receptor Signaling Pathway Cell Communication Signal Transduction Neurotrophin Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Response To Stimulus Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Death Positive Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Programmed Cell Death Regulation Of Metabolic Process Response To Stimulus Regulation Of MAP Kinase Activity Apoptotic Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Metabolic Process	Negative Regulation Of Cell Differentiation Stem Cell Development 7-methylguanosine MRNA Capping Transcription From RNA Polymerase II Promoter 7-methylguanosine RNA Capping Stem Cell Differentiation Positive Regulation Of Viral Transcription Regulation Of DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Hair Follicle Development Positive Regulation Of Gene Expression Hair Cycle Process Histone H3-K4 Acetylation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Hair Cycle Transcription, RNA-templated Positive Regulation Of Hemoglobin Biosynthetic Process Stem Cell Maintenance Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Defense Response To Nematode Gastrulation Transcription, DNA-templated Negative Regulation Of Vitamin D Biosynthetic Process Regulation Of Hemoglobin Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Nematode Positive Regulation Of Cellular Metabolic Process Epidermis Development Notch Signaling Involved In Heart Development Negative Regulation Of Erythrocyte Differentiation Regulation Of Tight Junction Assembly Positive Regulation Of Transcription, DNA-templated RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Cerebellar Purkinje Cell Differentiation RNA Metabolic Process
Tagcloud ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mst1 mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad
Tagcloud (Difference) ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mst1 mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad
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