MBP and STK26

Number of citations of the paper that reports this interaction (PMID 11641781)
15

Data Source:
HPRD (in vivo, in vitro)

		MBP	STK26
Gene Name		myelin basic protein	serine/threonine protein kinase 26
Image
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Internode Region Of Axon Neuronal Cell Body Compact Myelin	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Centrosome Cytosol Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Protease Binding Protein Binding Structural Constituent Of Myelin Sheath	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Immune Response Synaptic Transmission Central Nervous System Development Aging Axon Ensheathment Response To Toxic Substance Substantia Nigra Development Response To Progesterone Response To Tumor Necrosis Factor Myelination Response To Mercury Ion Negative Regulation Of Axonogenesis Membrane Organization Response To Fatty Acid	Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Microvillus Assembly Response To Hydrogen Peroxide Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Age-related macular degeneration (GA) ( 22705344)
Protein-Protein Interactions		72 interactors: ABL1 APTX ATN1 ATXN1 BMP2K CCNC CCNH CCNT1 CDK1 CDK12 CDK5 CDK7 CDK8 CDK9 CLK1 CTDSP1 DYRK1B HIPK2 HLA-DRA IKBKE IRAK1 IRAK4 LIMK1 LIMK2 LRRK2 MAG MAP3K3 MAP3K5 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPKAPK5 MELK MICU2 MKNK1 MMP7 MNAT1 NEK9 PAK1 PKN1 PLP1 PPP2R5C PRKACA PRKCA PRKCB PRKCD PRKCI PRKCZ PRKDC PRMT1 PRMT5 RAN RPS6KA5 RTN4 SQSTM1 SRPK1 STK16 STK26 STK3 STK39 STK4 TBK1 TLK1 TLK2 TRAF6 TRPM7 TSSK6 ULK1	7 interactors: APP GOLGA2 MBP NEDD4 PDCD10 RAF1 SRPK1
Entrez ID		4155	51765
HPRD ID		01158	06663
Ensembl ID		ENSG00000197971	ENSG00000134602
Uniprot IDs		P02686	B4E0Y9 Q8NBY1 Q9P289
PDB IDs		1BX2 1FV1 1HQR 1QCL 1YMM 1ZGL	3GGF 3W8I 4FZA 4FZD 4FZF 4GEH
Enriched GO Terms of Interacting Partners?		Protein Phosphorylation Phosphorylation Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Intracellular Signal Transduction Regulation Of Protein Phosphorylation Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Signal Transduction By Phosphorylation Protein Autophosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To Stress Regulation Of Protein Kinase Activity Peptidyl-threonine Phosphorylation Cellular Response To Growth Factor Stimulus Peptidyl-amino Acid Modification Regulation Of Protein Metabolic Process Response To Growth Factor Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway MAPK Cascade Cellular Response To Stress Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Phosphorylation Signaling Neurotrophin TRK Receptor Signaling Pathway Cell Communication Signal Transduction Neurotrophin Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Response To Stimulus Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Death Positive Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Programmed Cell Death Regulation Of Metabolic Process Response To Stimulus Regulation Of MAP Kinase Activity Apoptotic Process Cellular Response To Organic Substance Positive Regulation Of Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Metabolic Process	Immune Response Response To Stress Neuromuscular Junction Development Immune System Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Metabolic Process Locomotion Response To Inorganic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Death-inducing Signaling Complex Assembly Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Cellular Ketone Metabolic Process Defense Response Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Peptidyl-serine Phosphorylation Anatomical Structure Development Wound Healing Generation Of Neurons Regulation Of Cell Differentiation Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Synaptic Growth At Neuromuscular Junction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Neurogenesis Cell Activation Regulation Of Protein Binding Response To Wounding Regulation Of Neurogenesis Defense Response To Nematode Collateral Sprouting In Absence Of Injury Developmental Process Negative Regulation Of Cell Differentiation Regulation Of Protein Kinase Activity Cell Development Cell Differentiation Signaling Synapse Organization Golgi Reassembly Cell Communication Regulation Of Kinase Activity Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Negative Regulation Of Neuron Differentiation Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Intracellular Receptor Signaling Pathway
Tagcloud ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mst1 mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad
Tagcloud (Difference) ?		ac acetylcysteine antioxidants asp budding caspases ch2 cho cytotrienin dcb devd h2o2 hl immunologically krs1 krs2 mst1 mst2 myelin okadaic originally p36 peroxide programmed proteases ste20 streptomyces virtue yvad
Tagcloud (Intersection) ?