MATN4 and MATN3

Number of citations of the paper that reports this interaction (PubMedID 11896063)
0

Data Source:
HPRD (in vitro)

		MATN4	MATN3
Description		matrilin 4	matrilin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Matrilin Complex	Extracellular Region Endoplasmic Reticulum Lumen Extracellular Matrix Matrilin Complex
	Molecular Function	Calcium Ion Binding Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Extracellular Matrix Organization	Skeletal System Development Extracellular Matrix Organization Cartilage Development
Pathways		ECM proteoglycans	ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases			SEMD, Matrilin type; Spondyloepimetaphyseal dysplasia Multiple epiphyseal dysplasia (MED)
GWAS		Blood protein levels ( 30072576) Malaria ( 31844061)	Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		9 interacting genes: ACSF3 ENKD1 GORASP2 MATN1 MATN2 MATN3 NTAQ1 PPP1R13B SDCBP	6 interacting genes: INCA1 KRTAP10-8 MATN1 MATN4 NOTCH2NLA TCF4
Entrez ID		8785	4148
HPRD ID		04873	03661
Ensembl ID		ENSG00000124159	ENSG00000132031
Uniprot IDs		A2RRP8 A5D8U1 A6NNA4 B3KQB2 O95460	O15232
PDB IDs
Enriched GO Terms of Interacting Partners?		Matrilin Complex Extracellular Matrix Structural Constituent Extracellular Structure Organization Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Malonyl-CoA Synthetase Activity Malonate Catabolic Process Extracellular Matrix Dendrite Regeneration Interleukin-5 Receptor Binding Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding	Matrilin Complex Growth Plate Cartilage Chondrocyte Morphogenesis Calcium Ion Binding Beta-catenin-TCF7L2 Complex TFIIB-class Transcription Factor Binding Extracellular Structure Organization Extracellular Matrix Organization Cartilage Morphogenesis Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Beta-catenin-TCF Complex Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
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