CAMTA2 and ZNF483

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAMTA2	ZNF483
Description		calmodulin binding transcription activator 2	zinc finger protein 483
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Histone Deacetylase Binding Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998) Keratoconus ( 33649486)	Age at voice drop ( 27182965) Apolipoprotein A1 levels ( 32203549) Height ( 31562340) Menarche (age at onset) ( 21102462 23599027 25231870 27182965) Pubertal anthropometrics ( 23449627)
Interacting Genes		8 interacting genes: CALM1 CALM2 CALM3 HDAC5 MAGEA6 MEMO1 NKX2-5 ZNF483	11 interacting genes: APP CAMTA2 CRX ECPAS LBX1 MEOX2 TRIM69 USHBP1 ZKSCAN4 ZSCAN21 ZSCAN22
Entrez ID		23125	158399
HPRD ID		13002	18345
Ensembl ID		ENSG00000108509	ENSG00000173258
Uniprot IDs		I3L3W6 O94983	Q6P088 Q8TF39
PDB IDs			2CTU
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Regulation Of Cardiac Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Striated Muscle Contraction Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Calcium Channel Complex Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Muscle Contraction Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of Heart Contraction Sperm Midpiece Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcomere Cell Cycle G2/M Phase Transition Neural Nucleus Development Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Muscle System Process Regulation Of Blood Circulation Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Negative Regulation Of Voltage-gated Calcium Channel Activity Calcium-dependent Protein Binding Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Monoatomic Ion Transmembrane Transporter Activity	DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific Double-stranded DNA Binding Negative Regulation Of Glutamatergic Neuron Differentiation Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Gene Expression Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Chromatin Binding Astrocyte Activation Involved In Immune Response Positive Regulation Of DNA-templated Transcription Low-density Lipoprotein Particle Mediated Signaling DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Somite Specification Positive Regulation Of RNA Metabolic Process Chromatin Regulation Of Spontaneous Synaptic Transmission
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