MIR200A and SF3A3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR200A	SF3A3
Description		microRNA 200a	splicing factor 3a subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Amyloid-beta	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Appendicular lean mass ( 33097823) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 28869591 30598549) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		76 interacting genes: ADARB1 APOBEC3B C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NONO PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBM45 RTCA RTCB SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	38 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MIR106B MIR107 MIR141 MIR145 MIR155 MIR199A1 MIR200A MIR200C MIR206 MIR214 MIR221 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MTNR1B OGT PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212
Entrez ID		406983	10946
HPRD ID			10411
Ensembl ID		ENSG00000207607	ENSG00000183431
Uniprot IDs			B4DW90 Q12874
PDB IDs			2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y50 6Y53 6Y5Q 7ABG 7ABH 7ABI 7EVO 7ONB 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Macromolecule Metabolic Process Nucleus MiRNA Binding Nucleoplasm Negative Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Translation Catalytic Step 2 Spliceosome Spliceosomal Complex Cytoplasmic Stress Granule MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability Regulation Of Primary Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cytoplasmic Translation Regulation Of Metabolic Process Ligase Activity Negative Regulation Of Metabolic Process P-body	MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Negative Regulation Of Translation Extracellular Vesicle Regulation Of Translation Regulation Of Angiogenesis Negative Regulation Of Cell Migration MRNA Destabilization Regulation Of Vasculature Development Negative Regulation Of Cytokine Production RNA Destabilization Negative Regulation Of Cell Motility Regulation Of Gene Expression Negative Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Signal Transduction Regulation Of Connective Tissue Replacement Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Cytokine Production Positive Regulation Of Tissue Remodeling Regulation Of Macromolecule Metabolic Process Regulation Of Cell Motility Regulation Of MRNA Stability Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Programmed Cell Death Regulation Of Locomotion Negative Regulation Of Transport Regulation Of RNA Stability Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
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