LYZ and LTF

Number of citations of the paper that reports this interaction (PMID 9359845)
16

Data Source:
HPRD (in vitro)

		LYZ	LTF
Gene Name		lysozyme	lactotransferrin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Nucleus Secretory Granule Specific Granule Extracellular Vesicular Exosome Phagocytic Vesicle Lumen
	Molecular Function	Lysozyme Activity Identical Protein Binding	DNA Binding Serine-type Endopeptidase Activity Iron Ion Binding Protein Binding Ferric Iron Binding Heparin Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Retina Homeostasis Inflammatory Response Metabolic Process Cytolysis Defense Response To Bacterium	Ossification Regulation Of Cytokine Production Retina Homeostasis Innate Immune Response In Mucosa Transcription, DNA-templated Proteolysis Iron Ion Transport Humoral Immune Response Antibacterial Humoral Response Antifungal Humoral Response Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Tumor Necrosis Factor Production Iron Assimilation By Chelation And Transport Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Osteoblast Differentiation Positive Regulation Of NF-kappaB Transcription Factor Activity Interaction With Host Response To Host Immune Response Bone Morphogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Phagosome Maturation Positive Regulation Of Bone Mineralization Involved In Bone Maturation Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Positive Regulation Of Chondrocyte Proliferation Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Negative Regulation Of Osteoclast Development
Pathways		Amyloids	Amyloids Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Response of Mtb to phagocytosis Mtb iron assimilation by chelation
Drugs			3h-Indole-5,6-Diol Alpha-D-Mannose Nitrilotriacetic Acid Alpha-D-Fucose Nimesulide 2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE parecoxib
Diseases
GWAS		Height ( 18391951) Response to diuretic therapy ( 18591461)	AIDS progression ( 21502085)
Protein-Protein Interactions		6 interactors: A2M CLU ELN LCN1 LTF UBC	9 interactors: CALM1 CD14 CEL CP ITLN1 LCN1 LRP1 LYZ MUC7
Entrez ID		4069	4057
HPRD ID		01085	01028
Ensembl ID		ENSG00000090382	ENSG00000012223
Uniprot IDs		B2R4C5 P61626	E7ER44 P02788
PDB IDs		133L 134L 1B5U 1B5V 1B5W 1B5X 1B5Y 1B5Z 1B7L 1B7M 1B7N 1B7O 1B7P 1B7Q 1B7R 1B7S 1BB3 1BB4 1BB5 1C43 1C45 1C46 1C7P 1CJ6 1CJ7 1CJ8 1CJ9 1CKC 1CKD 1CKF 1CKG 1CKH 1D6P 1D6Q 1DI3 1DI4 1DI5 1EQ4 1EQ5 1EQE 1GAY 1GAZ 1GB0 1GB2 1GB3 1GB5 1GB6 1GB7 1GB8 1GB9 1GBO 1GBW 1GBX 1GBY 1GBZ 1GDW 1GDX 1GE0 1GE1 1GE2 1GE3 1GE4 1GEV 1GEZ 1GF0 1GF3 1GF4 1GF5 1GF6 1GF7 1GF8 1GF9 1GFA 1GFE 1GFG 1GFH 1GFJ 1GFK 1GFR 1GFT 1GFU 1GFV 1HNL 1I1Z 1I20 1I22 1INU 1IOC 1IP1 1IP2 1IP3 1IP4 1IP5 1IP6 1IP7 1IWT 1IWU 1IWV 1IWW 1IWX 1IWY 1IWZ 1IX0 1IY3 1IY4 1JKA 1JKB 1JKC 1JKD 1JSF 1JWR 1LAA 1LHH 1LHI 1LHJ 1LHK 1LHL 1LHM 1LMT 1LOZ 1LYY 1LZ1 1LZ4 1LZ5 1LZ6 1LZR 1LZS 1OP9 1OUA 1OUB 1OUC 1OUD 1OUE 1OUF 1OUG 1OUH 1OUI 1OUJ 1QSW 1RE2 1REM 1REX 1REY 1REZ 1TAY 1TBY 1TCY 1TDY 1UBZ 1W08 1WQM 1WQN 1WQO 1WQP 1WQQ 1WQR 1YAM 1YAN 1YAO 1YAP 1YAQ 207L 208L 2BQA 2BQB 2BQC 2BQD 2BQE 2BQF 2BQG 2BQH 2BQI 2BQJ 2BQK 2BQL 2BQM 2BQN 2BQO 2HEA 2HEB 2HEC 2HED 2HEE 2HEF 2LHM 2MEA 2MEB 2MEC 2MED 2MEE 2MEF 2MEG 2MEH 2MEI 2NWD 2ZIJ 2ZIK 2ZIL 2ZWB 3EBA 3FE0 3LHM 3LN2	1B0L 1BKA 1CB6 1DSN 1EH3 1FCK 1H43 1H44 1H45 1HSE 1L5T 1LCF 1LCT 1LFG 1LFH 1LFI 1LGB 1N76 1SQY 1U62 1VFD 1VFE 1XV4 1XV7 1Z6V 1Z6W 2BJJ 2DP4 2GMC 2GMD 2HD4 2PMS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteolysis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Catalytic Activity Retina Homeostasis Regulation Of Immune System Process Platelet Degranulation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokine Production Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Extracellular Matrix Disassembly Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Transferase Activity Iron Assimilation By Chelation And Transport Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Ubiquitination Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Antifungal Humoral Response Positive Regulation Of Bone Mineralization Involved In Bone Maturation Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Chondrocyte Proliferation Negative Regulation Of Osteoclast Development Negative Regulation Of Complement Activation, Lectin Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Protein Activation Cascade Negative Regulation Of Cellular Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Tissue Homeostasis Positive Regulation Of Phosphorylation Regulation Of Immune Response Central Nervous System Myelin Maintenance Platelet Activation	Positive Regulation Of Transport Retina Homeostasis Alcohol Metabolic Process Response To External Stimulus Phototransduction, Visible Light Beta-amyloid Clearance Protein Esterification Intestinal Lipid Catabolic Process Regulation Of Phospholipase Activity Detection Of Visible Light Phototransduction Detection Of Light Stimulus Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Multicellular Organismal Lipid Catabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Detection Of Abiotic Stimulus Response To Other Organism Tissue Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Biotic Stimulus Pancreatic Juice Secretion Response To Nematode Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Intestinal Cholesterol Absorption Multicellular Organismal Homeostasis Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Steroid Metabolic Process Phagocytosis Detection Of Calcium Ion Regulation Of Phospholipase A2 Activity Cholesterol Catabolic Process Lipid Digestion Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphoprotein Phosphatase Activity Lipid Transport Cellular Response To Lipoteichoic Acid Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Response To Metal Ion Lipid Localization Negative Regulation Of Smooth Muscle Cell Migration Response To Magnesium Ion Positive Regulation Of Nitric-oxide Synthase Activity Response To Abiotic Stimulus
Tagcloud ?		18mg 42days 42h 48h 5ml 60days 63mum ase biomimetic biopolymers bps chondroitin factor165 glycolic glycosaminoglycan hds hyaluronic incubating lds loading mgco3 microclimate microencapsulation microspheres percolating ph7 plga sink trehalose	ag alox15 basel caries childhood dentition ecc eec enam environmental experience fifty genotypes genotyping gg habits imbalance infectious karger klk4 protective rs1264848 rs198968 rs3790506 rs4547741 rs7217186 tt tuft1 unrelated
Tagcloud (Difference) ?		18mg 42days 42h 48h 5ml 60days 63mum ase biomimetic biopolymers bps chondroitin factor165 glycolic glycosaminoglycan hds hyaluronic incubating lds loading mgco3 microclimate microencapsulation microspheres percolating ph7 plga sink trehalose	ag alox15 basel caries childhood dentition ecc eec enam environmental experience fifty genotypes genotyping gg habits imbalance infectious karger klk4 protective rs1264848 rs198968 rs3790506 rs4547741 rs7217186 tt tuft1 unrelated
Tagcloud (Intersection) ?