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LTF and MUC7
Number of citations of the paper that reports this interaction (PubMedID
12766201
)
0
Data Source:
HPRD
(in vitro, in vivo)
LTF
MUC7
Description
lactotransferrin
mucin 7, secreted
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Early Endosome
Plasma Membrane
Cell Surface
Secretory Granule
Protein-containing Complex
Specific Granule Lumen
Specific Granule
Recycling Endosome
Extracellular Exosome
Phagocytic Vesicle Lumen
Tertiary Granule Lumen
Extracellular Region
Golgi Lumen
Plasma Membrane
Extracellular Exosome
Molecular Function
Lipopolysaccharide Binding
DNA Binding
Serine-type Endopeptidase Activity
Cysteine-type Endopeptidase Inhibitor Activity
Iron Ion Binding
Protein Binding
Heparin Binding
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Protein Serine/threonine Kinase Activator Activity
Metal Ion Binding
Membrane Destabilizing Activity
Protein Binding
Biological Process
Ossification
Regulation Of Cytokine Production
Innate Immune Response In Mucosa
Immune System Process
Proteolysis
Monoatomic Ion Transport
Iron Ion Transport
Humoral Immune Response
Antibacterial Humoral Response
Antifungal Humoral Response
Killing Of Cells Of Another Organism
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of ATP-dependent Activity
Positive Regulation Of Osteoblast Proliferation
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Defense Response To Bacterium
Negative Regulation Of Apoptotic Process
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Host-mediated Suppression Of Viral Proces
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Osteoblast Differentiation
Negative Regulation Of Membrane Potential
Negative Regulation Of Viral Process
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cytolysis By Host Of Symbiont Cells
Bone Morphogenesis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Bone Mineralization Involved In Bone Maturation
Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism
Positive Regulation Of Chondrocyte Proliferation
Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production
Negative Regulation Of Osteoclast Development
Killing Of Cells Of Another Organism
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways
Mtb iron assimilation by chelation
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Antimicrobial peptides
Amyloid fiber formation
Defective GALNT3 causes HFTC
Defective C1GALT1C1 causes TNPS
Defective GALNT12 causes CRCS1
Dectin-2 family
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis
Drugs
3h-Indole-5,6-Diol
Lauric acid
Nitrilotriacetic acid
alpha-D-Fucopyranose
Nimesulide
(R)-Atenolol
Parecoxib
Diseases
GWAS
AIDS progression (
21502085
)
Cerebrospinal fluid levels of Alzheimer's disease-related proteins (
25340798
)
Early-onset schizophrenia (
33907183
)
Inflammatory bowel disease (
26192919
)
Macular thickness (
30535121
)
Ulcerative colitis (
26192919
)
Diabetic nephropathy in type 1 diabetes (
31537649
)
Interacting Genes
13 interacting genes:
ACE2
CALM1
CD14
CEL
CP
EPPIN
ITLN1
LCN1
LRP1
LYZ
MUC7
UBC
USP7
8 interacting genes:
AMY1A
GALNT10
GALNT12
GALNT14
HTN3
LTF
PCGF1
SELL
Entrez ID
4057
4589
HPRD ID
01028
11759
Ensembl ID
ENSG00000012223
ENSG00000171195
Uniprot IDs
B3KSL2
E7ER44
P02788
Q2TUW9
V9HWI4
Q8TAX7
PDB IDs
1B0L
1BKA
1CB6
1DSN
1EH3
1FCK
1H43
1H44
1H45
1HSE
1L5T
1LCF
1LCT
1LFG
1LFH
1LFI
1LGB
1N76
1SQY
1U62
1VFD
1VFE
1XV4
1XV7
1Z6V
1Z6W
2BJJ
2DP4
2GMC
2GMD
2HD4
2PMS
7JRD
7N88
Enriched GO Terms of Interacting Partners
?
Extracellular Region
Extracellular Space
Endocytic Vesicle Membrane
Extracellular Exosome
Regulation Of Transport
Endocytosis
Receptor-mediated Endocytosis
Negative Regulation Of Calcium Ion Transport
Membrane Raft
Opsonin Receptor Activity
Oxidoreductase Activity, Acting On Metal Ions, Oxygen As Acceptor
Positive Regulation Of Transcytosis
Alpha-2 Macroglobulin Receptor Activity
Apolipoprotein Receptor Activity
Brush Border Membrane
Import Into Cell
Negative Regulation Of High Voltage-gated Calcium Channel Activity
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Response To Other Organism
Diterpenoid Metabolic Process
Retinoid Metabolic Process
Acetylesterase Activity
Oxidoreductase Activity, Acting On Metal Ions
Positive Regulation Of Reverse Cholesterol Transport
Regulation Of Transcytosis
Positive Regulation Of L-proline Import Across Plasma Membrane
Angiotensin-mediated Drinking Behavior
Peptidyl-dipeptidase Activity
Regulation Of Cardiac Muscle Contraction
Phagocytosis
Cellular Response To Triacyl Bacterial Lipopeptide
Response To External Biotic Stimulus
Terpenoid Metabolic Process
Ceramide Metabolic Process
Ferroxidase Activity
Lipoprotein Particle Receptor Binding
Symbiont-mediated Disruption Of Host Cell PML Body
Negative Regulation Of Flagellated Sperm Motility
Entry Receptor-mediated Virion Attachment To Host Cell
Negative Regulation Of Monoatomic Ion Transport
Regulation Of Striated Muscle Contraction
Lipopolysaccharide Receptor Complex
Positive Regulation Of Transport
Peptidoglycan Immune Receptor Activity
Sterol Ester Esterase Activity
Isoprenoid Metabolic Process
Phospholipid-hydroperoxide Glutathione Peroxidase Activity
Astrocyte Activation Involved In Immune Response
Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Viral Translation
Polypeptide N-acetylgalactosaminyltransferase Activity
Protein O-linked Glycosylation Via N-acetyl-galactosamine
Carbohydrate Binding
Metal Ion Binding
Protein O-linked Glycosylation
Protein Glycosylation
Macromolecule Glycosylation
Glycosylation
Glycosyltransferase Activity
Glycoprotein Biosynthetic Process
Glycoprotein Metabolic Process
Defense Response To Fungus
Response To Fungus
Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production
Alpha-amylase Activity
Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism
Carbohydrate Derivative Biosynthetic Process
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Killing Of Cells Of Another Organism
Positive Regulation Of Bone Mineralization Involved In Bone Maturation
Phagocytic Vesicle Lumen
Membrane Destabilizing Activity
Antimicrobial Humoral Response
Heparin Binding
Negative Regulation Of Osteoclast Development
Golgi Membrane
Extracellular Space
Glycosphingolipid Binding
Cell Killing
Positive Regulation Of Chondrocyte Proliferation
Regulation Of Osteoclast Development
Carbohydrate Derivative Metabolic Process
Cytolysis By Host Of Symbiont Cells
Antifungal Humoral Response
Chloride Ion Binding
Humoral Immune Response
Negative Regulation Of ATP-dependent Activity
Negative Regulation Of Membrane Potential
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Osteoblast Proliferation
Oligosaccharide Binding
Specific Granule
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Cation Binding
Host-mediated Suppression Of Viral Proces
Defense Response To Bacterium
Tagcloud
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Tagcloud (Intersection)
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