LTBP3 and GORASP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LTBP3	GORASP2
Gene Name		latent transforming growth factor beta binding protein 3	golgi reassembly stacking protein 2, 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Matrix Extracellular Vesicular Exosome	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Calcium Ion Binding Transforming Growth Factor Beta Binding	Protein Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Matrix Organization Negative Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Transforming Growth Factor Beta Activation Positive Regulation Of Bone Resorption Bone Remodeling Bone Morphogenesis Lung Saccule Development Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Mesenchymal Stem Cell Differentiation	Mitotic Cell Cycle Organelle Organization
Pathways		Molecules associated with elastic fibres Elastic fibre formation	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Urate levels ( 23263486)	Cognitive performance ( 19734545)
Protein-Protein Interactions		12 interactors: CACNA1A CCNG1 GORASP2 HBEGF ITGB5 PELI2 PIK3R2 PRPF40A RAC1 TGFB1 TGFB2 TGFB3	69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148
Entrez ID		4054	26003
HPRD ID		03649	08303
Ensembl ID		ENSG00000168056	ENSG00000115806
Uniprot IDs		B9EG76 Q8WYU6 Q9NS15	B4DKT0 B4DNR1 Q9H8Y8
PDB IDs			3RLE 4EDJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macrophage Cytokine Production Cellular Response To Growth Factor Stimulus Response To Growth Factor SMAD Protein Import Into Nucleus Cell Growth Regulation Of Cell Morphogenesis Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Wound Healing Uterine Wall Breakdown Tissue Remodeling Response To Wounding Positive Regulation Of Epithelial To Mesenchymal Transition Transforming Growth Factor Beta Receptor Signaling Pathway Face Morphogenesis Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Kinase Activity Positive Regulation Of Cell Morphogenesis Involved In Differentiation Head Morphogenesis Head Development Positive Regulation Of Intracellular Signal Transduction Blood Coagulation Ossification Involved In Bone Remodeling Hemostasis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Migration Salivary Gland Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Salivary Gland Development Cell Surface Receptor Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Response To Transforming Growth Factor Beta Platelet Activation Frontal Suture Morphogenesis Response To Progesterone Regulation Of Phosphorus Metabolic Process Face Development Cell Motility Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Growth SMAD Protein Signal Transduction Negative Regulation Of Cytokine Production Regulation Of Epithelial To Mesenchymal Transition Cell-cell Junction Organization Regulation Of Lipid Kinase Activity Bone Remodeling Exocrine System Development Body Morphogenesis	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization
Tagcloud ?		albeit causal contributor correlates define differ differing doi dx ecm egln1 elife http identifies mammary matrix metastatic org proteomics s100a2 serve signatures sned1 steps stroma stromal tgfbeta tools xenografts
Tagcloud (Difference) ?		albeit causal contributor correlates define differ differing doi dx ecm egln1 elife http identifies mammary matrix metastatic org proteomics s100a2 serve signatures sned1 steps stroma stromal tgfbeta tools xenografts
Tagcloud (Intersection) ?