LTBP3

Gene Name		latent transforming growth factor beta binding protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Transforming Growth Factor Beta Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Matrix Organization Negative Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Transforming Growth Factor Beta Activation Positive Regulation Of Bone Resorption Bone Remodeling Bone Morphogenesis Lung Saccule Development Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways		Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Urate levels ( 23263486)
Protein-protein Interactions		12 interactors: CACNA1A CCNG1 GORASP2 HBEGF ITGB5 PELI2 PIK3R2 PRPF40A RAC1 TGFB1 TGFB2 TGFB3
Entrez ID		4054
HPRD ID		03649
Ensembl ID		ENSG00000168056
Uniprot IDs		B9EG76 Q8WYU6 Q9NS15
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macrophage Cytokine Production Cellular Response To Growth Factor Stimulus Response To Growth Factor SMAD Protein Import Into Nucleus Cell Growth Regulation Of Cell Morphogenesis Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Wound Healing Uterine Wall Breakdown Tissue Remodeling Response To Wounding Positive Regulation Of Epithelial To Mesenchymal Transition Transforming Growth Factor Beta Receptor Signaling Pathway Face Morphogenesis Regulation Of Immune System Process Regulation Of Phosphorylation Regulation Of Kinase Activity Positive Regulation Of Cell Morphogenesis Involved In Differentiation Head Morphogenesis Head Development Positive Regulation Of Intracellular Signal Transduction Blood Coagulation Ossification Involved In Bone Remodeling Hemostasis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Migration Salivary Gland Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Salivary Gland Development Cell Surface Receptor Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Response To Transforming Growth Factor Beta Platelet Activation Frontal Suture Morphogenesis Response To Progesterone Regulation Of Phosphorus Metabolic Process Face Development Cell Motility Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Growth SMAD Protein Signal Transduction Negative Regulation Of Cytokine Production Regulation Of Epithelial To Mesenchymal Transition Cell-cell Junction Organization Regulation Of Lipid Kinase Activity Bone Remodeling Exocrine System Development Body Morphogenesis
Tagcloud ?		albeit causal contributor correlates define differ differing doi dx ecm egln1 elife http identifies mammary matrix metastatic org proteomics s100a2 serve signatures sned1 steps stroma stromal tgfbeta tools xenografts