MAGEA8 and ZNF221

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA8	ZNF221
Description		MAGE family member A8	zinc finger protein 221
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Histone Deacetylase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Serum immune biomarker levels ( 32066700)
Interacting Genes		15 interacting genes: BEX5 CCDC59 GCA LMO2 LXN MAGEB4 MLH1 MTUS2 PKD2 TDRD7 UBE3A WT1 ZNF221 ZNF224 ZNF417	3 interacting genes: KRTAP10-6 MAGEA8 MDFI
Entrez ID		4107	7638
HPRD ID		02278	10323
Ensembl ID		ENSG00000156009	ENSG00000159905
Uniprot IDs		B2R9W4 P43361	Q9UK13
PDB IDs		8FJB
Enriched GO Terms of Interacting Partners?		Metanephric S-shaped Body Morphogenesis S-shaped Body Morphogenesis Metanephric Mesenchyme Development Metanephric Epithelium Development Renal Tubule Morphogenesis Regulation Of Transcription By RNA Polymerase II Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Branching Involved In Ureteric Bud Morphogenesis Metanephric Cortical Collecting Duct Development Metanephric Cortex Development Metanephric Distal Tubule Development Mesonephric Epithelium Development Mesonephric Tubule Development Sperm Entry Positive Regulation Of Golgi Lumen Acidification Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Polycystin Complex Metanephric Smooth Muscle Tissue Development Cellular Response To CAMP Mesenchyme Development Renal Artery Morphogenesis Kidney Epithelium Development Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Male Meiosis Chromosome Segregation MutLalpha Complex Cellular Response To Hydrostatic Pressure Detection Of Nodal Flow Regulation Of Golgi Lumen Acidification Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Response To CAMP Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Guanine/thymine Mispair Binding Homologous Chromosome Segregation
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