MAGEA8 and GCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA8	GCA
Description		MAGE family member A8	grancalcin
Image
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Histone Deacetylase Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Membrane Fusion
Pathways			Neutrophil degranulation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		15 interacting genes: BEX5 CCDC59 GCA LMO2 LXN MAGEB4 MLH1 MTUS2 PKD2 TDRD7 UBE3A WT1 ZNF221 ZNF224 ZNF417	15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 CALCOCO2 CSTPP1 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3
Entrez ID		4107	25801
HPRD ID		02278	06122
Ensembl ID		ENSG00000156009	ENSG00000115271
Uniprot IDs		B2R9W4 P43361	B7Z322 H7BXD5 P28676
PDB IDs		8FJB	1F4O 1F4Q 1K94 1K95
Enriched GO Terms of Interacting Partners?		Metanephric S-shaped Body Morphogenesis S-shaped Body Morphogenesis Metanephric Mesenchyme Development Metanephric Epithelium Development Renal Tubule Morphogenesis Regulation Of Transcription By RNA Polymerase II Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Branching Involved In Ureteric Bud Morphogenesis Metanephric Cortical Collecting Duct Development Metanephric Cortex Development Metanephric Distal Tubule Development Mesonephric Epithelium Development Mesonephric Tubule Development Sperm Entry Positive Regulation Of Golgi Lumen Acidification Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Polycystin Complex Metanephric Smooth Muscle Tissue Development Cellular Response To CAMP Mesenchyme Development Renal Artery Morphogenesis Kidney Epithelium Development Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Male Meiosis Chromosome Segregation MutLalpha Complex Cellular Response To Hydrostatic Pressure Detection Of Nodal Flow Regulation Of Golgi Lumen Acidification Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Response To CAMP Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Guanine/thymine Mispair Binding Homologous Chromosome Segregation	Thioesterase Binding
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