KATNA1 and CAMSAP3

Number of citations of the paper that reports this interaction (PubMedID 29395789)
0

Data Source:
BioGRID (pull down)

		KATNA1	CAMSAP3
Description		katanin catalytic subunit A1	calmodulin regulated spectrin associated protein family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton Midbody Mitotic Spindle Mitotic Spindle Pole	Cytoplasm Centrosome Cytoskeleton Microtubule Adherens Junction Zonula Adherens Axoneme Microtubule Cytoskeleton Replication Fork Protection Complex Motile Cilium Ciliary Basal Body Microtubule Minus-end Cell Projection Anchoring Junction
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity Protein Heterodimerization Activity	DNA Binding Protein Binding Calmodulin Binding Microtubule Binding Spectrin Binding Microtubule Minus-end Binding Actin Filament Binding
	Biological Process	Cytoplasmic Microtubule Organization Microtubule Severing Cell Division	DNA Replication Checkpoint Signaling Microtubule Cytoskeleton Organization In Utero Embryonic Development Cilium Movement Embryo Development Ending In Birth Or Egg Hatching Cell Projection Organization Regulation Of Cell Migration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Regulation Of Microtubule Polymerization Neuron Projection Development Regulation Of Organelle Organization Microtubule Anchoring Replication Fork Arrest Establishment Of Epithelial Cell Apical/basal Polarity Zonula Adherens Maintenance Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Epithelial Cell-cell Adhesion Protein Transport Along Microtubule Regulation Of Golgi Organization
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Lung cancer ( 27393504) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 28604728)	Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes		11 interacting genes: APP CAMSAP3 CLK1 CLU DCAF1 DYNC1H1 DYRK2 KATNB1 LIPE OGT PAFAH1B1	7 interacting genes: DHX15 FSD2 GSK3B HSF2BP KATNA1 KATNB1 TUBB3
Entrez ID		11104	57662
HPRD ID		05986	13871
Ensembl ID		ENSG00000186625	ENSG00000076826
Uniprot IDs		A8K7S5 O75449	Q9P1Y5
PDB IDs		5ZQL 5ZQM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nitric Oxide Biosynthetic Process Transport Along Microtubule Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Nitric Oxide Metabolic Process Microtubule-based Movement Regulation Of Microtubule Cytoskeleton Organization Regulation Of Nitric Oxide Biosynthetic Process Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Regulation Of Nitric Oxide Metabolic Process Cytoplasmic Microtubule Organization Cytoskeleton Axo-dendritic Transport Regulation Of Microtubule-based Process Centrosome Intracellular Signal Transduction Regulation Of Amyloid Fibril Formation Protein Heterodimerization Activity Microtubule Regulation Of Amyloid-beta Clearance Regulation Of Protein Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Retrograde Axonal Transport Ether Lipid Metabolic Process Dynein Complex Binding Regulation Of Supramolecular Fiber Organization Protein-containing Complex Growth Cone Microtubule-based Process Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of MiRNA Transcription Nuclear Migration Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of Signal Transduction Positive Regulation Of Supramolecular Fiber Organization Microglial Cell Activation Microtubule Cytoskeleton Organization Nucleus Localization Hemopoiesis Leukocyte Activation Involved In Inflammatory Response Negative Regulation Of Signaling Negative Regulation Of Cell Communication Dynein Intermediate Chain Binding Supramolecular Fiber Organization Regulation Of Toll-like Receptor Signaling Pathway Nuclear Estrogen Receptor Binding Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Regulation Of Cytoskeleton Organization	Katanin Complex Microtubule Severing Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Binding Regulation Of Microtubule-based Process Microtubule Cytoskeleton Regulation Of Microtubule Anchoring At Centrosome Excitatory Postsynaptic Potential Hepatocyte Growth Factor Receptor Activity Cytoplasmic Microtubule Organization Microtubule Nucleotide Binding Axon Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity ATPase Regulator Activity Netrin Receptor Binding Regulation Of Postsynaptic Membrane Potential Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Cytoskeleton Organization U2-type Post-mRNA Release Spliceosomal Complex Positive Regulation Of Organelle Organization Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Cytoskeleton Organization Regulation Of Glycogen (starch) Synthase Activity Pyrimidine Dimer Repair By Nucleotide-excision Repair Post-embryonic Camera-type Eye Morphogenesis Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity Positive Regulation Of Microtubule Depolymerization Mitotic Chromosome Movement Towards Spindle Pole Growth Cone Mitotic Spindle Dorsal Root Ganglion Development Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Spindle Pole Positive Regulation Of Protein Localization To Cilium Microtubule Severing ATPase Activity Cellular Response To Interleukin-3 Positive Regulation Of Protein Localization To Centrosome Post-embryonic Eye Morphogenesis Positive Regulation Of Supramolecular Fiber Organization Female Meiosis I ATP Binding Centrosome
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