LGALS8 and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LGALS8	TAX1BP1
Gene Name		lectin, galactoside-binding, soluble, 8	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane Extracellular Vesicular Exosome	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding	Protein Binding Kinase Binding
	Biological Process	Plasma Cell Differentiation T Cell Costimulation	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APEH BARD1 CALCOCO2 ITGA3 ITGA4 ITGB1 MID2 TAX1BP1 TRIM23	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		3964	8887
HPRD ID		09356	05618
Ensembl ID		ENSG00000116977	ENSG00000106052
Uniprot IDs		O00214	A4D196 B4DSG5 Q86VP1
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4FQZ 4GXL 4HAN
Enriched GO Terms of Interacting Partners?		Integrin-mediated Signaling Pathway Leukocyte Tethering Or Rolling Formation Of Primary Germ Layer Negative Regulation Of Rho Protein Signal Transduction Cell-matrix Adhesion Heterotypic Cell-cell Adhesion Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Immune System Process Response To Stress Positive Regulation Of Protein Localization To Plasma Membrane Gastrulation Cell-substrate Adhesion Cellular Extravasation Mesodermal Cell Differentiation Leukocyte Migration Response To Gonadotropin Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Extracellular Matrix Organization Extracellular Structure Organization Maternal Process Involved In Female Pregnancy Blood Coagulation Hemostasis Mesoderm Formation Mesoderm Morphogenesis B Cell Differentiation Heart Development Negative Regulation Of MRNA 3'-end Processing Cell-matrix Adhesion Involved In Ameboidal Cell Migration Positive Regulation Of Cell-substrate Adhesion Viral Process Defense Response Protein Ubiquitination Regulation Of Body Fluid Levels Regulation Of Collagen Catabolic Process Negative Regulation Of Cell Projection Organization Wound Healing Response To Stimulus Protein Modification By Small Protein Conjugation Mesoderm Development Embryonic Morphogenesis Negative Regulation Of Protein Homodimerization Activity Calcium-independent Cell-matrix Adhesion B Cell Activation Regulation Of Locomotion Regulation Of Establishment Of Protein Localization Formation Of Radial Glial Scaffolds Response To Wounding	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?		antigens arrays auc autoantibodies autoantibody diagnostics discriminate discriminatory earliest engineered eventually facile harbored ideally igg igm libraries otud6b pdhx probed questioned receiver rodent sera stk39 syngeneic tgmmtv vps35 zpf238	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?		antigens arrays auc autoantibodies autoantibody diagnostics discriminate discriminatory earliest engineered eventually facile harbored ideally igg igm libraries otud6b pdhx probed questioned receiver rodent sera stk39 syngeneic tgmmtv vps35 zpf238	100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?