LGALS8 and TRIM49

Number of citations of the paper that reports this interaction (PubMedID 27693506)
53

Data Source:
BioGRID (pull down)

		LGALS8	TRIM49
Description		galectin 8	tripartite motif containing 49
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	Cytoplasm
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Plasma Cell Differentiation Autophagy T Cell Costimulation Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Regulation Of Gene Expression Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Intraocular pressure ( 30591961) Response to taxane treatment (docetaxel) ( 23006423) Serum metabolite levels ( 33031748)
Interacting Genes		22 interacting genes: ANXA1 APEH BARD1 CALCOCO2 ERBB2 G3BP1 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 NUFIP2 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2	4 interacting genes: BLM LGALS8 MINDY3 POM121
Entrez ID		3964	57093
HPRD ID		09356	05840
Ensembl ID		ENSG00000116977	ENSG00000168930
Uniprot IDs		O00214	E9PK69 P0CI25
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z 6Z6Y 7AEN 7ALS 7P1M 8CM8 8HL9 9FYJ
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Innate Immune Response Immune System Process Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Autophagy Immune Response Positive Regulation Of Metabolic Process Defense Response Regulation Of Metabolic Process Response To Other Organism Integrin Alpha3-beta1 Complex Response To External Biotic Stimulus Integrin Alpha4-beta1 Complex Metal Ion Binding Positive Regulation Of Catabolic Process Integrin Complex Positive Regulation Of Macromolecule Metabolic Process Cytoplasm Response To Stress Regulation Of Autophagy Fibronectin Binding Protein Ubiquitination Zinc Ion Binding Regulation Of Protein Localization C-X3-C Chemokine Binding Protein Modification Process Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Defense Response To Virus Cell-cell Adhesion Mediated By Integrin Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Coreceptor Activity Regulation Of Defense Response Post-translational Protein Modification Positive Regulation Of Gene Expression Regulation Of Intracellular Signal Transduction Negative Regulation Of Vasoconstriction Response To Virus Neuromuscular Junction Mesodermal Cell Differentiation Protein-macromolecule Adaptor Activity Focal Adhesion Transferase Activity Regulation Of Rho Protein Signal Transduction Suppression Of Viral Release By Host Positive Regulation Of Immune System Process	8-hydroxy-2'-deoxyguanosine DNA Binding DNA Geometric Change Forked DNA-dependent Helicase Activity Resolution Of DNA Recombination Intermediates Telomeric G-quadruplex DNA Binding DNA/DNA Annealing Activity RecQ Family Helicase-topoisomerase III Complex Telomeric D-loop Binding Four-way Junction Helicase Activity Telomeric D-loop Disassembly Cellular Response To Camptothecin Bubble DNA Binding Y-form DNA Binding G-quadruplex DNA Binding Telomere Maintenance Via Semi-conservative Replication Lymphatic Endothelial Cell Migration Xenophagy Plasma Cell Differentiation Nuclear Membrane T-circle Formation Cellular Response To Hydroxyurea Response To Hydroxyurea Telomeric Loop Disassembly Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides 3'-5' DNA Helicase Activity Lateral Element Negative Regulation Of Cell Division Four-way Junction DNA Binding DNA Conformation Change K48-linked Deubiquitinase Activity Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding DNA Double-strand Break Processing
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?