LGALS8 and NACC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LGALS8	NACC1
Description		galectin 8	nucleus accumbens associated 1
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytoplasm Cell Junction Nuclear Lumen
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Histone Deacetylase Binding
	Biological Process	Plasma Cell Differentiation Autophagy T Cell Costimulation Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Obesity-related traits ( 23251661)
Interacting Genes		22 interacting genes: ANXA1 APEH BARD1 CALCOCO2 ERBB2 G3BP1 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 NUFIP2 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2	20 interacting genes: BCOR C8orf33 CCNB1 EHHADH ELOA HDAC3 HDAC4 LGALS8 LSM3 PML POLR2L PRKCI PRPF18 PRPF3 SENP1 SENP2 TARDBP UBE2I UBTFL1 ZNF512B
Entrez ID		3964	112939
HPRD ID		09356	10692
Ensembl ID		ENSG00000116977	ENSG00000160877
Uniprot IDs		O00214	Q96RE7
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z 6Z6Y 7AEN 7ALS 7P1M 8CM8 8HL9 9FYJ	3GA1 4U2N 7BV9 8YZS
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Innate Immune Response Immune System Process Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Autophagy Immune Response Positive Regulation Of Metabolic Process Defense Response Regulation Of Metabolic Process Response To Other Organism Integrin Alpha3-beta1 Complex Response To External Biotic Stimulus Integrin Alpha4-beta1 Complex Metal Ion Binding Positive Regulation Of Catabolic Process Integrin Complex Positive Regulation Of Macromolecule Metabolic Process Cytoplasm Response To Stress Regulation Of Autophagy Fibronectin Binding Protein Ubiquitination Zinc Ion Binding Regulation Of Protein Localization C-X3-C Chemokine Binding Protein Modification Process Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Defense Response To Virus Cell-cell Adhesion Mediated By Integrin Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Coreceptor Activity Regulation Of Defense Response Post-translational Protein Modification Positive Regulation Of Gene Expression Regulation Of Intracellular Signal Transduction Negative Regulation Of Vasoconstriction Response To Virus Neuromuscular Junction Mesodermal Cell Differentiation Protein-macromolecule Adaptor Activity Focal Adhesion Transferase Activity Regulation Of Rho Protein Signal Transduction Suppression Of Viral Release By Host Positive Regulation Of Immune System Process	Protein Sumoylation Nucleoplasm Regulation Of RNA Metabolic Process SUMO Transferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process U4/U6 X U5 Tri-snRNP Complex SUMO-specific Endopeptidase Activity Nucleus DeSUMOylase Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Desumoylation Histone Deacetylase Activity, Hydrolytic Mechanism Regulation Of Gene Expression RNA Metabolic Process Protein Deacetylation Protein Lysine Deacetylase Activity Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Transcription By RNA Polymerase I Negative Regulation Of Myotube Differentiation Histone Deacetylase Activity Negative Regulation Of Macromolecule Metabolic Process PML Body Regulation Of Circadian Rhythm Negative Regulation Of Macromolecule Biosynthetic Process Maintenance Of Protein Location In Nucleus Macromolecule Deacylation Negative Regulation Of Metabolic Process Positive Regulation Of Post-translational Protein Modification Histone Deacetylase Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Presynaptic Cytosol Postsynaptic Cytosol Positive Regulation Of MRNA Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process RNA Splicing Regulation Of Protein Stability Response To DDT Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Interleukin-1 Production Negative Regulation Of Translation In Response To Oxidative Stress Negative Regulation Of Catabolic Process Maintenance Of Protein Localization In Organelle Regulation Of Transcription By RNA Polymerase I SUMO Conjugating Enzyme Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?