NACC1 and BCOR

Number of citations of the paper that reports this interaction (PMID 19121354)
14

Data Source:
BioGRID (two hybrid)

		NACC1	BCOR
Gene Name		nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	BCL6 corepressor
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body Cell Junction Intracellular Membrane-bounded Organelle	Nucleus PcG Protein Complex
	Molecular Function		Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K36 Methylation Transcription, DNA-templated Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Palate Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Pit-and-Fissure caries ( 23470693)
Protein-Protein Interactions		4 interactors: BCOR HDAC3 HDAC4 TARDBP	17 interactors: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF3 PCGF5 SP1 UBTD1 USP7
Entrez ID		112939	54880
HPRD ID		10692	06458
Ensembl ID		ENSG00000160877	ENSG00000183337
Uniprot IDs		Q96RE7	Q6W2J9
PDB IDs		3GA1	3BIM 4HPL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Histone H4 Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H3 Deacetylation Histone H3-K9 Modification Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Protein Deacetylation Negative Regulation Of Ossification Negative Regulation Of Cellular Metabolic Process Chromatin Modification Transcription, DNA-templated Chromatin Organization RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K36 Methylation Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Tooth Mineralization RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Ossification Negative Regulation Of Nucleic Acid-templated Transcription Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Specification Of Axis Polarity Negative Regulation Of Odontogenesis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Transport Negative Regulation Of Histone H3-K4 Methylation Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Inactivity 3'-UTR-mediated MRNA Stabilization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation By Host Of Viral Transcription	Histone H4 Deacetylation Histone H3 Deacetylation Histone H3-K9 Modification Histone Deacetylation Protein Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Histone Modification RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Modification Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression, Epigenetic Peptidyl-lysine Deacetylation Positive Regulation Of Receptor Biosynthetic Process Negative Regulation Of Myotube Differentiation B Cell Differentiation Regulation Of Receptor Biosynthetic Process Regulation Of Skeletal Muscle Fiber Development Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process B Cell Activation Osteoblast Development Positive Regulation Of Macromolecule Biosynthetic Process Organelle Organization Cellular Metabolic Process
Tagcloud ?			aa acquisition aging asxl1 attrition bonafide clonal context critically dnmt3a dysregulation especially evolution exome explored haemopoiesis hierarchical infancy nearly points predicting regulators replicative sampling sequencing serial still telomere unbiased
Tagcloud (Difference) ?			aa acquisition aging asxl1 attrition bonafide clonal context critically dnmt3a dysregulation especially evolution exome explored haemopoiesis hierarchical infancy nearly points predicting regulators replicative sampling sequencing serial still telomere unbiased
Tagcloud (Intersection) ?