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LAMC2 and SLA2
Number of citations of the paper that reports this interaction (PubMedID
17353186
)
0
Data Source:
BioGRID
(far western blotting)
LAMC2
SLA2
Description
laminin subunit gamma 2
Src like adaptor 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Basement Membrane
Laminin-2 Complex
Extracellular Space
Cell Cortex
Extracellular Matrix
Perinuclear Region Of Cytoplasm
Nucleoplasm
Cytoplasm
Late Endosome
Golgi Apparatus
Cytosol
Plasma Membrane
Endosome Membrane
Endomembrane System
Membrane
Cytoplasmic Vesicle
Molecular Function
Extracellular Matrix Structural Constituent
Heparin Binding
Protein Binding
Signaling Adaptor Activity
Biological Process
Cell Adhesion
Positive Regulation Of Cell Population Proliferation
Epidermis Development
Positive Regulation Of Cell Migration
Negative Regulation Of Transcription By RNA Polymerase II
B Cell Mediated Immunity
T Cell Activation
Regulation Of Immune Response
Negative Regulation Of Calcium-mediated Signaling
Antigen Receptor-mediated Signaling Pathway
Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Anchoring fibril formation
Laminin interactions
Laminin interactions
Non-integrin membrane-ECM interactions
Type I hemidesmosome assembly
MET activates PTK2 signaling
Attachment of bacteria to epithelial cells
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Developmental Lineage of Pancreatic Ductal Cells
Negative regulation of FLT3
Drugs
Diseases
Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS
Acne (severe) (
30542056
)
Blood protein levels (
30072576
)
Clozapine-induced agranulocytosis (
25187353
)
HDL cholesterol (
21347282
)
Low density lipoprotein cholesterol levels (
32154731
)
Morning person (
30696823
)
Systemic lupus erythematosus (
21408207
)
Interacting Genes
7 interacting genes:
BMP1
COL7A1
CSF1R
FBLN2
LAMB3
NID1
SLA2
16 interacting genes:
CBL
CD247
CSF1
EGFR
EPHA4
ERBB2
ERBB3
ERBB4
GAB1
KIT
LAMC2
MAP1LC3A
MET
PRKAA2
UBASH3A
ZAP70
Entrez ID
3918
84174
HPRD ID
01031
05955
Ensembl ID
ENSG00000058085
ENSG00000101082
Uniprot IDs
Q13753
Q9H6Q3
PDB IDs
4M4Z
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix
Basement Membrane
Extracellular Matrix Structural Constituent
Extracellular Matrix Binding
Endodermal Cell Differentiation
Collagen Type VII Trimer
SREBP-SCAP Complex
CSF1-CSF1R Complex
Macrophage Colony-stimulating Factor Receptor Activity
Response To Vitamin B3
Extracellular Region
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Protein Kinase Activity
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Kinase Activity
Enzyme-linked Receptor Protein Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Basal Plasma Membrane
ERBB2 Signaling Pathway
Regulation Of Intracellular Signal Transduction
ERBB Signaling Pathway
Positive Regulation Of Signal Transduction
Receptor Complex
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Signal Transduction
Positive Regulation Of MAPK Cascade
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Transferase Activity
Positive Regulation Of Locomotion
ERBB3:ERBB2 Complex
Regulation Of Cell Migration
ATP Binding
Regulation Of MAPK Cascade
Regulation Of Cell Motility
Regulation Of Programmed Cell Death
Regulation Of Locomotion
Epidermal Growth Factor Receptor Activity
Neuregulin Receptor Activity
Positive Regulation Of Protein Metabolic Process
Regulation Of Cell Population Proliferation
Negative Regulation Of Apoptotic Process
Nucleotide Binding
Protein Tyrosine Kinase Binding
Cell Migration
Intracellular Signal Transduction
Positive Regulation Of Phosphate Metabolic Process
ErbB-3 Class Receptor Binding
ERBB2-ERBB4 Signaling Pathway
Growth Factor Binding
Tagcloud
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Tagcloud (Difference)
?
Tagcloud (Intersection)
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