SLA2

Description		Src like adaptor 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Late Endosome Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Signaling Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II B Cell Mediated Immunity T Cell Activation Regulation Of Immune Response Negative Regulation Of Calcium-mediated Signaling Antigen Receptor-mediated Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways		Negative regulation of FLT3
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CBL CD247 CSF1 EGFR EPHA4 ERBB2 ERBB3 ERBB4 GAB1 KIT LAMC2 MAP1LC3A MET PRKAA2 UBASH3A ZAP70
Entrez ID		84174
HPRD ID		05955
Ensembl ID		ENSG00000101082
Uniprot IDs		Q9H6Q3
PDB IDs		4M4Z
Enriched GO Terms of Interacting Partners?		Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane ERBB2 Signaling Pathway Regulation Of Intracellular Signal Transduction ERBB Signaling Pathway Positive Regulation Of Signal Transduction Receptor Complex Negative Regulation Of Programmed Cell Death Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Transferase Activity Positive Regulation Of Locomotion ERBB3:ERBB2 Complex Regulation Of Cell Migration ATP Binding Regulation Of MAPK Cascade Regulation Of Cell Motility Regulation Of Programmed Cell Death Regulation Of Locomotion Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Nucleotide Binding Protein Tyrosine Kinase Binding Cell Migration Intracellular Signal Transduction Positive Regulation Of Phosphate Metabolic Process ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Growth Factor Binding
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