SUMO1P1 and UBA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SUMO1P1	UBA2
Description		SUMO1 pseudogene 1	ubiquitin like modifier activating enzyme 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Nucleus Nucleoplasm Nucleolus Cytoplasm SUMO Activating Enzyme Complex
	Molecular Function	Protein Binding Transcription Factor Binding Protein Tag Activity Identical Protein Binding Ubiquitin-like Protein Ligase Binding	Nucleotide Binding Magnesium Ion Binding Protein Binding ATP Binding Ubiquitin-like Modifier Activating Enzyme Activity Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Protein Sumoylation PML Body Organization	Protein Sumoylation Positive Regulation Of Protein Sumoylation
Pathways			SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS		Copper levels ( 26025379) Cortical volume ( 32963231) Polycystic ovary syndrome ( 22885925)
Interacting Genes		33 interacting genes: ACTN3 ARK2N AXIN1 CKS1B EDARADD ESRRG FAM118B FAM200A FHL2 FKBP6 GMCL1 HNRNPC KRTAP9-2 L3MBTL3 LCE2A LCE2D MAPK1IP1L NAB2 PHC1 PIAS1 PIAS2 SATB1 SETBP1 SOX5 STX1A SUMO1 TRAF2 TRIM23 UBA2 UBE2I ZBTB26 ZBTB6 ZNRD2	19 interacting genes: BRIX1 CEBPA CHEK1 ERCC6 ETV4 MEOX2 NEDD8 PARK7 RAD23B SAE1 SERBP1 SETX SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBD UBE2I
Entrez ID		391257	10054
HPRD ID			11658
Ensembl ID			ENSG00000126261
Uniprot IDs			Q9UBT2
PDB IDs			1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ 6XOG 6XOH 6XOI
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Identical Protein Binding Small Protein Activating Enzyme Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process PML Body Negative Regulation Of Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Transcription Factor Binding SUMO Transferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Post-translational Protein Modification Presynaptic Cytosol Postsynaptic Cytosol Transcription Corepressor Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Ubiquitin Protein Ligase Binding SUMO Ligase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Calcineurin-NFAT Signaling Cascade Protein Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Positive Regulation Of Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteolysis Nuclear Body Negative Regulation Of Calcium-mediated Signaling Chromatin Organization Regulation Of Protein Sumoylation Enzyme Binding Synaptonemal Complex Positive Regulation Of Proteasomal Protein Catabolic Process Chromatin Remodeling Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate	Protein Tag Activity Small Protein Activating Enzyme Binding Protein Sumoylation Protein Modification By Small Protein Conjugation PML Body Post-translational Protein Modification Nucleus Ubiquitin-like Protein Ligase Binding PML Body Organization Protein Modification Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Macromolecule Metabolic Process Protein Metabolic Process Nuclear Body Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Transcription Factor Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Nucleus Organization Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Protein Metabolic Process DNA Repair Regulation Of Protein Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II DNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Binding DNA Damage Response Proteasome Binding Negative Regulation Of DNA Binding Ubiquitin-specific Protease Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Metabolic Process SUMO Transferase Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Sumoylation Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Binding Modification-dependent Protein Catabolic Process Nucleolus Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?