SUMO1P1 and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SUMO1P1	FKBP6
Description		SUMO1 pseudogene 1	FKBP prolyl isomerase family member 6 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Synaptonemal Complex Fibrillar Center Nucleus Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Protein Binding Transcription Factor Binding Protein Tag Activity Identical Protein Binding Ubiquitin-like Protein Ligase Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Protein Sumoylation PML Body Organization	Protein Folding Spermatogenesis Cell Differentiation Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle Transposable Element Silencing By PiRNA-mediated DNA Methylation
Pathways			Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Copper levels ( 26025379) Cortical volume ( 32963231) Polycystic ovary syndrome ( 22885925)	Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		33 interacting genes: ACTN3 ARK2N AXIN1 CKS1B EDARADD ESRRG FAM118B FAM200A FHL2 FKBP6 GMCL1 HNRNPC KRTAP9-2 L3MBTL3 LCE2A LCE2D MAPK1IP1L NAB2 PHC1 PIAS1 PIAS2 SATB1 SETBP1 SOX5 STX1A SUMO1 TRAF2 TRIM23 UBA2 UBE2I ZBTB26 ZBTB6 ZNRD2	38 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CFTR CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 RAB11FIP2 RNF4 SAXO4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		391257	8468
HPRD ID			05326
Ensembl ID			ENSG00000077800
Uniprot IDs			O75344
PDB IDs			3B7X
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Identical Protein Binding Small Protein Activating Enzyme Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process PML Body Negative Regulation Of Metabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Transcription Factor Binding SUMO Transferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Post-translational Protein Modification Presynaptic Cytosol Postsynaptic Cytosol Transcription Corepressor Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Ubiquitin Protein Ligase Binding SUMO Ligase Activity Positive Regulation Of Protein Sumoylation Negative Regulation Of Calcineurin-NFAT Signaling Cascade Protein Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Positive Regulation Of Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteolysis Nuclear Body Negative Regulation Of Calcium-mediated Signaling Chromatin Organization Regulation Of Protein Sumoylation Enzyme Binding Synaptonemal Complex Positive Regulation Of Proteasomal Protein Catabolic Process Chromatin Remodeling Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate	Shelterin Complex Telomere Assembly Meiotic DNA Double-strand Break Formation Protein Binding Regulation Of Telomere Maintenance Via Telomerase Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region
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