MAFA and MAF

Number of citations of the paper that reports this interaction (PMID 12011435)
79

Data Source:
HPRD (in vitro)

		MAFA	MAF
Gene Name		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Chromatin Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Sequence-specific DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nitric Oxide Mediated Signal Transduction Response To Glucose Insulin Secretion Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cytokine Production Transcription From RNA Polymerase II Promoter Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Inner Ear Development Lens Fiber Cell Differentiation
Pathways		Regulation of beta-cell development Regulation of gene expression in beta cells
Drugs
Diseases
GWAS			Height ( 20668459) Multiple sclerosis ( 21833088) Obesity ( 19151714) Renal function-related traits (urea) ( 22797727) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid volume ( 21565293) Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: MAF MAPK1 MAPK14 NEUROD1 PDX1	15 interactors: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB SMARCA5 SOX9 USF2
Entrez ID		389692	4094
HPRD ID		14346	01518
Ensembl ID		ENSG00000182759	ENSG00000178573
Uniprot IDs		Q8NHW3	O75444
PDB IDs		4EOT
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Tissue Development Nitric Oxide Mediated Signal Transduction Transcription, DNA-templated Enteroendocrine Cell Differentiation RNA Biosynthetic Process Organ Morphogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Localization Epithelium Development Positive Regulation Of DNA Binding Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Lipopolysaccharide-mediated Signaling Pathway Insulin Secretion Organ Development Glandular Epithelial Cell Differentiation RNA Metabolic Process Toll-like Receptor 5 Signaling Pathway Endocrine Pancreas Development Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Differentiation Positive Regulation Of Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Gene Expression MyD88-independent Toll-like Receptor Signaling Pathway Peptide Hormone Secretion Toll-like Receptor 3 Signaling Pathway Peptide Secretion Cellular Macromolecule Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Epithelial Cell Differentiation Hormone Secretion Regulation Of DNA Binding Regulation Of Intracellular Signal Transduction Hormone Transport Peptide Transport Pancreas Development Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Embryo Development Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus Gland Development Positive Regulation Of Metabolic Process Response To Stress Multicellular Organismal Development N-terminal Peptidyl-lysine Acetylation Anatomical Structure Development Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Response To Abiotic Stimulus Response To Cytokine Cellular Metabolic Process Regulation Of Myeloid Cell Differentiation Response To Oxidative Stress Response To Organic Substance Developmental Process Response To Reactive Oxygen Species Regulation Of Immune System Process Response To Extracellular Stimulus
Tagcloud ?		2h3 antisense attaining bonds capable cdna cloned clustering conservation cysteinyl deduced disulfide epsilon fc g63 glycoprotein homology immunomodulatory intrachain lectin mast named novo oligonucleotides rbl ri secretory stimulus though	belongs chicken cnc conceivably consists dimeric disrupt erythroid erythroleukemia erythropoiesis exclusively globin integration kda lcrs leucine mast mega p45 pharmacologic polycythemia progenitors red retroviral substitute thrombocytopenia trilineage vera zipper
Tagcloud (Difference) ?		2h3 antisense attaining bonds capable cdna cloned clustering conservation cysteinyl deduced disulfide epsilon fc g63 glycoprotein homology immunomodulatory intrachain lectin named novo oligonucleotides rbl ri secretory stimulus though	belongs chicken cnc conceivably consists dimeric disrupt erythroid erythroleukemia erythropoiesis exclusively globin integration kda lcrs leucine mega p45 pharmacologic polycythemia progenitors red retroviral substitute thrombocytopenia trilineage vera zipper
Tagcloud (Intersection) ?		mast