MAFA

Description		MAF bZIP transcription factor A
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GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Glucose Insulin Secretion Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of gene expression in beta cells
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Nonsyndromic cleft palate ( 31609978)
Interacting Genes		6 interacting genes: HERC4 MAF MAPK1 MAPK14 NEUROD1 PDX1
Entrez ID		389692
HPRD ID		14346
Ensembl ID		ENSG00000182759
Uniprot IDs		Q8NHW3
PDB IDs		4EOT
Enriched GO Terms of Interacting Partners?		Transcription By RNA Polymerase II Negative Regulation Of Type B Pancreatic Cell Apoptotic Process DNA-templated Transcription Cell Differentiation Response To Nutrient Levels Enteroendocrine Cell Differentiation MAP Kinase Activity Endocrine Pancreas Development Cellular Developmental Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Protein Transport Response To Lipid Lipopolysaccharide-mediated Signaling Pathway Nucleobase-containing Compound Biosynthetic Process Response To Nicotine Positive Regulation Of Nucleobase-containing Compound Metabolic Process Insulin Secretion Positive Regulation Of Establishment Of Protein Localization Regulation Of Epithelial Cell Apoptotic Process Inner Ear Development Epithelial Cell Differentiation Peptide Hormone Secretion Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Transport Positive Regulation Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Acadesine Embryonic Morphogenesis Sequence-specific DNA Binding Positive Regulation Of Insulin Secretion DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Peptide Secretion Regulation Of Ossification Regulation Of Cellular Localization Stem Cell Differentiation Animal Organ Development Homeostatic Process Regulation Of Establishment Of Protein Localization Anatomical Structure Morphogenesis Ficolin-1-rich Granule Lumen Negative Regulation Of Signaling Positive Regulation Of Biosynthetic Process Negative Regulation Of Signal Transduction Response To Peptide Response To Tumor Necrosis Factor RNA Metabolic Process Macromolecule Metabolic Process
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