VTI1B and TRIM59

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VTI1B	TRIM59
Gene Name		vesicle transport through interaction with t-SNAREs 1B	tripartite motif containing 59
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Intracellular Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity	Zinc Ion Binding
	Biological Process	Autophagic Vacuole Fusion Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Cell Proliferation Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Protein Localization To Plasma Membrane	Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: GOLGB1 KRTAP10-7 LDLRAD1 PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59	6 interactors: ECSIT ESR1 ESR2 NRM VTI1B ZDHHC22
Entrez ID		10490	286827
HPRD ID		04440	15568
Ensembl ID		ENSG00000100568	ENSG00000213186
Uniprot IDs		Q9UEU0	Q8IWR1
PDB IDs		2V8S
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Membrane Fusion Vesicle Organization Vesicle Docking Positive Regulation Of Receptor Localization To Synapse Membrane Docking Positive Regulation Of Eosinophil Degranulation Vesicle-mediated Transport Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Protein Localization Membrane Organization Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Protein Transport Positive Regulation Of Immunoglobulin Secretion SNARE Complex Assembly Establishment Of Monopolar Cell Polarity Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Cellular Localization Regulation Of Clathrin-mediated Endocytosis Regulation Of Immunoglobulin Secretion Establishment Of Epithelial Cell Polarity Regulation Of Vesicle-mediated Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Early Endosome To Late Endosome Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Hydroperoxide Organelle Localization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Morphogenesis Of A Polarized Epithelium Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Localization Positive Regulation Of Protein Localization To Plasma Membrane Protein Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Endosome To Lysosome Transport Establishment Of Protein Localization Intracellular Transport Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immunoglobulin Production Regulation Of Regulated Secretory Pathway Organelle Organization	Vagina Development Uterus Development Intracellular Estrogen Receptor Signaling Pathway Female Genitalia Development Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Genitalia Development Ovarian Follicle Development Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Oxidoreductase Activity Ovulation Cycle Process Steroid Hormone Mediated Signaling Pathway Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Tissue Morphogenesis Hormone-mediated Signaling Pathway Gland Morphogenesis Prostate Epithelial Cord Elongation Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Epithelial Cell Development Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Epithelial Cell Maturation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Hormone-mediated Apoptotic Signaling Pathway DNA-templated Transcription, Initiation Gonad Development Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Development Of Primary Sexual Characteristics Golgi To Vacuole Transport Regulation Of Branching Involved In Prostate Gland Morphogenesis Vesicle Fusion With Golgi Apparatus Mammary Gland Branching Involved In Pregnancy Sex Differentiation Rhythmic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Negative Regulation Of Androgen Receptor Signaling Pathway Urogenital System Development Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Epithelial Cell Differentiation Involved In Prostate Gland Development Extracellular Negative Regulation Of Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Cellular Response To Estradiol Stimulus
Tagcloud ?		autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative snare snares vacuole vacuoles vamp3 vamp7 vamp8 vti1a	affiliated ags arrays bgc823 carcinogenesis clone gastric ges immunoblotting interacted knocked ligase messenger mkn45 n87 nanchang nontumor nude oncomine opposite physically renji sets sgc7901 snu1 snu5 tripartite ubiquitination xenograft
Tagcloud (Difference) ?		autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative snare snares vacuole vacuoles vamp3 vamp7 vamp8 vti1a	affiliated ags arrays bgc823 carcinogenesis clone gastric ges immunoblotting interacted knocked ligase messenger mkn45 n87 nanchang nontumor nude oncomine opposite physically renji sets sgc7901 snu1 snu5 tripartite ubiquitination xenograft
Tagcloud (Intersection) ?