VTI1B and STX7

Number of citations of the paper that reports this interaction (PMID 12114520)
17

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		VTI1B	STX7
Gene Name		vesicle transport through interaction with t-SNAREs 1B	syntaxin 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Tertiary Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Autophagic Vacuole Fusion Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Cell Proliferation Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Protein Localization To Plasma Membrane	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: GOLGB1 KRTAP10-7 LDLRAD1 PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59	13 interactors: ENTPD2 MAPK6 NAPA SNAP29 STX4 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B
Entrez ID		10490	8417
HPRD ID		04440	04449
Ensembl ID		ENSG00000100568
Uniprot IDs		Q9UEU0	O15400
PDB IDs		2V8S
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Membrane Fusion Vesicle Organization Vesicle Docking Positive Regulation Of Receptor Localization To Synapse Membrane Docking Positive Regulation Of Eosinophil Degranulation Vesicle-mediated Transport Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Protein Localization Membrane Organization Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Protein Transport Positive Regulation Of Immunoglobulin Secretion SNARE Complex Assembly Establishment Of Monopolar Cell Polarity Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Cellular Localization Regulation Of Clathrin-mediated Endocytosis Regulation Of Immunoglobulin Secretion Establishment Of Epithelial Cell Polarity Regulation Of Vesicle-mediated Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Early Endosome To Late Endosome Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Hydroperoxide Organelle Localization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Morphogenesis Of A Polarized Epithelium Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Localization Positive Regulation Of Protein Localization To Plasma Membrane Protein Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Endosome To Lysosome Transport Establishment Of Protein Localization Intracellular Transport Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immunoglobulin Production Regulation Of Regulated Secretory Pathway Organelle Organization	Vesicle Fusion Membrane Fusion Organelle Fusion Protein Transport Establishment Of Protein Localization Vesicle Organization Protein Localization Intracellular Protein Transport Establishment Of Localization In Cell Vesicle-mediated Transport Intracellular Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Golgi Vesicle Transport Membrane Organization Cellular Protein Localization SNARE Complex Assembly Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Vesicle-mediated Transport Endosomal Transport Secretion By Cell Positive Regulation Of Regulated Secretory Pathway Secretion Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Cellular Component Organization Transport Regulation Of Protein Localization Positive Regulation Of Exocytosis Regulation Of SNARE Complex Assembly Autophagic Vacuole Fusion Vesicle Fusion With Golgi Apparatus Regulation Of Cellular Localization Vacuolar Transport Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Docking Positive Regulation Of Mast Cell Degranulation Interaction With Host Positive Regulation Of Hormone Secretion Positive Regulation Of Mast Cell Activation Cellular Protein Complex Assembly Organelle Organization Regulation Of Mast Cell Degranulation Endosome To Lysosome Transport
Tagcloud ?		autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative snare snares vacuole vacuoles vamp3 vamp7 vamp8 vti1a	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Difference) ?		autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative vacuole vacuoles vamp7 vamp8 vti1a	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vesicle
Tagcloud (Intersection) ?		snare snares vamp3 vti1b